MedPath

CSTONE PHARMA-B

🇭🇰Hong Kong, China
Ownership
-
Established
2018-12-13
Employees
164
Market Cap
-
Website
http://www.cstonepharma.com
Introduction

Cornerstone Pharmaceutical was created to meet the needs of cancer patients and focuses on developing and commercializing innovative tumor immunotherapy and molecular-targeted drugs. Since its establishment 3 years ago, the company has assembled a world-class management team with rich experience in preclinical research, clinical development and commercialization.

Through a dual source of innovation consisting of internal R&D and external collaboration, the company has built a powerful anti-tumor drug pipeline with 14 drug candidates, including 4 products exclusively collaborated and authorized by Blueprint Medicine and Agios Pharmaceuticals. Together with the self-developed pipeline, the company has significant potential and synergistic effects for single and combination therapies. Of the drug candidates under development, 4 are in or close to critical trials. Cornerstone Pharmaceutical's business model is driven by clinical research and development, while rapidly establishing commercialization and production capacity.

The company received support from well-known investors, and both the A and B rounds of financing broke records in the biomedical field at the time, with a total amount of 412 million US dollars in the two rounds of financing.

With an experienced team, a promising R&D pipeline, a strong business model, and sustainable financial support, Cornerstone's vision is to become a world-renowned leading Chinese biopharmaceutical company by bringing innovative and differentiated oncology therapies to cancer patients around the world.

A Phase I Study of CS2009 in Participants With Advanced Solid Tumors

Phase 1
Recruiting
Conditions
Advanced Solid Tumors
Interventions
First Posted Date
2024-12-19
Last Posted Date
2025-03-07
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
230
Registration Number
NCT06741644
Locations
🇨🇳

Linyi Cancer Hospital, Linyi, China

🇨🇳

Shanghai East Hospital, Shanghai, China

🇦🇺

Alfred Hospital (Alfred Health), Melbourne, Australia

and more 19 locations

Study of Sugemalimab (or Placebo) Plus PGemOx Regimen in Participants With Extranodal NK/T-Cell Lymphoma

Phase 3
Not yet recruiting
Conditions
Extranodal NK/T-cell Lymphoma
Interventions
First Posted Date
2023-01-26
Last Posted Date
2025-01-01
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
150
Registration Number
NCT05700448

Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World

First Posted Date
2022-05-19
Last Posted Date
2024-11-13
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
61
Registration Number
NCT05381753
Locations
🇨🇳

Beijing Cancer Hospital, Beijing, Beijing, China

A Study of Lorlatinib in Subjects With ROS1-Positive Non-Small Cell Lung Cancer

Phase 2
Active, not recruiting
Conditions
Advanced or Metastatic ROS1-Positive Non-Small Cell Lung Cancer
Interventions
First Posted Date
2022-03-28
Last Posted Date
2025-05-02
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
70
Registration Number
NCT05297890
Locations
🇨🇳

Hunan Cancer Hospital, Changsha, China

🇨🇳

Sichuan Cancer Hospital & Institute, Chengdu, China

🇨🇳

West China Hospital of Sichuan University, Chengdu, China

and more 28 locations

A Study of CS5001 in Patients With Advanced Solid Tumors and Lymphomas

Phase 1
Recruiting
Conditions
Advanced Solid Tumor
Advanced Lymphoma
Interventions
First Posted Date
2022-03-15
Last Posted Date
2025-04-10
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
156
Registration Number
NCT05279300
Locations
🇨🇳

First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

🇦🇺

Epworth Foundation trading as Epworth HealthCare, Melbourne, Victoria, Australia

🇨🇳

Sun YatSen University Cancer Center, Guangzhou, Guang Dong, China

and more 29 locations

Safety and Tolerability Evaluation of Low-dose Radiation in Combination With CS1001 in Relapsed SCLC Patients

Phase 1
Completed
Conditions
Relapsed Small Cell Lung Cancer
Interventions
First Posted Date
2020-06-09
Last Posted Date
2024-03-07
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
11
Registration Number
NCT04421352
Locations
🇨🇳

West China Hospital, Sichuan University, Chendu, Sichuan, China

A Phase I Study of CS1002 in Subjects With Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumor
Interventions
First Posted Date
2020-04-08
Last Posted Date
2021-02-21
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
6
Registration Number
NCT04338724
Locations
🇨🇳

Henan Cancer Hospital, Zhengzhou, Henan, China

A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor

Phase 1
Completed
Conditions
Gastrointestinal Stromal Tumors
Interventions
Drug: CS3007 (BLU-285)
First Posted Date
2020-02-05
Last Posted Date
2023-04-27
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
65
Registration Number
NCT04254939
Locations
🇨🇳

The First Affiliated Hospital of Nanchang Medical University, Nanchang, Jiangxi, China

🇨🇳

Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China

🇨🇳

Wuhan Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, China

and more 13 locations

A Study of CS3005 in Advanced Solid Tumors

Phase 1
Completed
Conditions
Advanced Solid Tumor
Interventions
First Posted Date
2020-01-18
Last Posted Date
2022-04-27
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
9
Registration Number
NCT04233060
Locations
🇦🇺

Scientia Clinical Research Ltd, Sydney, New South Wales, Australia

A Study of CS1001 in Combination With Regorafenib in Patients With Advanced or Refractory Solid Tumors

Phase 1
Completed
Conditions
Advanced Refractory Solid Tumors
Interventions
First Posted Date
2019-12-16
Last Posted Date
2022-05-06
Lead Sponsor
CStone Pharmaceuticals
Target Recruit Count
19
Registration Number
NCT04200404
Locations
🇦🇺

Ashford Cancer Centre Research, Kurralta Park, South Australia, Australia

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