High-density EEG in Neurological Disorders
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Epilepsy
- Sponsor
- Dartmouth-Hitchcock Medical Center
- Enrollment
- 122
- Locations
- 1
- Primary Endpoint
- Localizing Brain Regions That Generate Interictal Spikes
- Status
- Completed
- Last Updated
- 4 months ago
Overview
Brief Summary
The purpose of the study is to use a new method of high-density electroencephalogram (HD-EEG) recording to map brain areas important for movement, sensation, language, emotion, and cognition.
Detailed Description
This study will measure brain waves using high-density EEG. Participants will be asked wear a cap with electrodes attached to it. During the recording, participants may be asked to rest, sleep, or complete a task. The tasks involve viewing pictures, answering questions, speaking, or moving an arm or leg. Recordings generally last between 60-120 minutes.\*
Investigators
Yinchen Song
Clinical Neurophysiologist, Neuro Diagnostics
Dartmouth-Hitchcock Medical Center
Eligibility Criteria
Inclusion Criteria
- •Able to perform the tasks
- •Able to give own consent
Exclusion Criteria
- •Any neurologic or psychiatric diagnosis such as stroke, tumor, or psychosis judged to interfere with high-density EEG.
Outcomes
Primary Outcomes
Localizing Brain Regions That Generate Interictal Spikes
Time Frame: From 30-60 min HD-EEG recording, pre-operatively
The frequency of detecting interictal spikes in HD-EEG The distance between the source location determined by electrical source imaging and the spike locations determined by SEEG studies
Secondary Outcomes
- Localize Brain Functions in Patients and Healthy Controls(At baseline for approximately 60 - 90 minutes)
- Localize Brain Areas Involved in Language(At baseline for approximately 60 - 90 minutes)
- Localize Brain Areas Involved in Movement(At baseline for approximately 60 - 90 minutes)
- Localize Brain Areas Involved in Sensation(At baseline for approximately 60 - 90 minutes)
- Localize Brain Areas Associated With Lesions(At baseline for approximately 60 - 90 minutes)