High-density EEG in Neurological Disorders

Not Applicable

• Conditions: Epilepsy; Healthy; Tumor

• Registration Number: NCT04266041
• Lead Sponsor: Dartmouth-Hitchcock Medical Center

Brief Summary

The purpose of the study is to use a new method of high-density electroencephalogram (HD-EEG) recording to map brain areas important for movement, sensation, language, emotion, and cognition.

Detailed Description

This study will measure brain waves using high-density EEG. Participants will be asked wear a cap with electrodes attached to it. During the recording, participants may be asked to rest, sleep, or complete a task. The tasks involve viewing pictures, answering questions, speaking, or moving an arm or leg. Recordings generally last between 60-120 minutes.\*

Study Timeline

• Study Start: 2018-02-09
• Study First Submitted: 2020-02-10
• Study First Submitted QC: 2020-02-10
• Study First Posted: 2020-02-12
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-07
• Last Update Posted: 2025-02-11
• Primary Completion: 2028-02-09
• Study Completion: 2028-03-09

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Able to perform the tasks
• Able to give own consent

Exclusion Criteria

• Any neurologic or psychiatric diagnosis such as stroke, tumor, or psychosis judged to interfere with high-density EEG.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Localize brain functions in patients and healthy controls	At baseline for approximately 60 - 90 minutes	Localize brain functions using high-density EEG recordings

Secondary Outcome Measures

Name	Time	Method
Localize brain areas involved in sensation	At baseline for approximately 60 - 90 minutes	Localize brain areas involved in sensation using high-density EEG recordings
Localize brain areas involved in emotion	At baseline for approximately 60 - 90 minutes	Localize brain areas involved in emotion using high-density EEG recordings
Localize brain areas associated with lesions	At baseline for approximately 60 - 90 minutes	Localize brain areas associated with lesions using high-density EEG recordings
Localize brain areas involved in movement	At baseline for approximately 60 - 90 minutes	Localize brain areas involved in movement using high-density EEG recordings
Localize brain areas involved in language	At baseline for approximately 60 - 90 minutes	Localize brain areas involved in language using high-density EEG recordings
Localize brain areas involved in memory	At baseline for approximately 60 - 90 minutes	Localize brain areas involved in memory using high-density EEG recordings

Trial Locations

Locations (1)

Dartmouth-Hitchcock Medical Center; 🇺🇸 Lebanon, New Hampshire, United States