Periodontopathogens of Periodontal Patients

Not Applicable

Recruiting

• Conditions: Periodontal Diseases

• Registration Number: NCT05940714
• Lead Sponsor: University of Barcelona

Brief Summary

Study the presence of periodontal pathogens in a Catalan population with periodontitis and evaluate the influence of an intervention measure on oral hygiene teaching (video)

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-15
• Study First Submitted: 2023-06-14
• Status Verified: 2023-07
• Study First Submitted QC: 2023-07-03
• Last Update Submitted: 2023-07-03
• Study First Posted: 2023-07-11
• Last Update Posted: 2023-07-11
• Primary Completion: 2023-11-15
• Study Completion: 2024-10-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Patients over 18 years of age
• periodontal disease (grade III and IV)
• gave their informed consent to participate in the study
• do not present associated medical pathology

Exclusion Criteria

• Patients who do not wish to participate in the study
• Patients following active treatment with antibiotics or having received antibiotic treatment in the last seven days,
• Patients who wear braces.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Presence of periodontopathogens	1 month	Study the presence of periodontogens in a Catalan population with periodontitis and evaluate the influence of an intervention measure in the form of oral hygiene education.

Secondary Outcome Measures

Name	Time	Method
Correlate the level of periodontal disease with the patient's oral health.	1 month	Classification established in the World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions
Correlate variations in the levels of pro-inflammatory cytokines with the patient's systemic diseases.	1 month	Measurement through ELISA/cytometry test and search for quantitative changes and review of the clinical history
Correlate the microbiota and pro-inflammatory cytokine data obtained in the study population with the literature.	1 month	Measure through conventional and molecular microbiological study of bacteria, looking for changes in the total count and measurement of cytokine through ELISA/cytometry test and search for quantitative changes
Determine if there are changes in the oral microbiota, before and after an intervention in the form of oral hygiene.	1 month	Measure through conventional and molecular microbiological study of bacteria, looking for changes in the total count
Determine if there are changes in the levels of pro-inflammatory cytokines, before and after an intervention measure in the form of oral hygiene.	1 month	Measurement through ELISA/cytometry test and search for quantitative changes
Correlate the level of periodontal disease with the patient's systemic diseases	1 month	Classification established in the World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions and review of the clinical history
Correlate the variations in the oral microbiota with the patient's systemic diseases.	1 month	Measure through conventional and molecular microbiological study of bacteria, looking for changes in the total count and review of the clinical history

Trial Locations

Locations (1)

University of Barcelona; 🇪🇸 Hospitalet de Llobregat, Barcelona, Spain