Prevalence of Macrovascular Disease in Type 2 Diabetes Mellitus: Left Ventricular Diastolic Dysfunction, Myocardial Ischemia and Peripheral Vascular Insufficient

Odense University Hospital1 site in 1 country350 target enrollmentJanuary 2006

ConditionsType 2 Diabetes Mellitus

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Type 2 Diabetes Mellitus
Sponsor: Odense University Hospital
Enrollment: 350
Locations: 1
Last Updated: 19 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The study aim is to establish a consecutive population of newly referred type 2 diabetes mellitus patients and among these to describe the degree of macrovascular disease by evaluating left ventricular systolic and diastolic function (echocardiography), myocardial perfusion (single-photon emission computed tomography (SPECT)), the peripheral vascular perfusion (strain gauge toe blood pressure measurements and a ultrasound scan of the a. carotis communis). Further, the degree of microvascular disease will be evaluated (glomerular filtration rate assessment, fundus photography and biotesiometry). Finally the cohort will be followed the next two years to assess the prognostic value of the above-mentioned parameters

Registry

clinicaltrials.gov

Start Date

January 2006

End Date

January 2010

Last Updated

19 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Odense University Hospital

Eligibility Criteria

Inclusion Criteria

•Age: ≥ 20 years.
•Fasting C-peptide \> 300 pmol/l.

Exclusion Criteria

•Verified medical history of macrovascular disease (stroke, myocardiac infarct, coronary revascularisation or strain gauge toe blood pressure \< 30 mmHg).
•Suspected short lifespan because of malignant disease or end-stage kidney disease.
•Pregnancy or planned pregnancy during the study period.
•Body weight \> 150 kg.
•Physical or mental disability not enabling participation in the study.