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Clinical Trials/NCT03786406
NCT03786406
Completed
Not Applicable

A Non-interventional Cross-sectional Study to Capture the Prevalence of Cardiovascular Disease in Patients With Type 2 Diabetes in Selected Countries in Europe

Novo Nordisk A/S1 site in 1 country2,275 target enrollmentDecember 3, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diabetes Mellitus, Type 2
Sponsor
Novo Nordisk A/S
Enrollment
2275
Locations
1
Primary Endpoint
Diagnosed with peripheral artery disease: Asymptomatic peripheral arterial disease (PAD) defined as Low Ankle-Brachial Index (less than 0.90) or pulse abolition, claudication, limb ischemia and/or non-traumatic amputation
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of the study is to register the occurrence of cardiovascular disease among type 2 diabetes (T2DM) patients across five selected countries in Europe. Participants will be asked to give information about their health. Participants will continue their normal way of life and will not get any medication other than what has been prescribed to them by their doctor. Participants' participation will be one day/one visit at study doctor. The study will last for about 3 months in total.

Registry
clinicaltrials.gov
Start Date
December 3, 2018
End Date
May 31, 2019
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Signed informed consent obtained before any study-related activities (study-related activities are any procedures related to recording of data according to protocol)
  • Male or female, age greater than or equal to 18 years at the time of signing informed consent
  • Diagnosed with type 2 diabetes mellitus greater than or equal to 180 days prior to the day of signing the informed consent

Exclusion Criteria

  • Previous participation in this study. Participation is defined as having given informed consent in this study
  • Diagnosed with Type 1 diabetes
  • Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation
  • Patients with known congenital heart disease/malformation

Outcomes

Primary Outcomes

Diagnosed with peripheral artery disease: Asymptomatic peripheral arterial disease (PAD) defined as Low Ankle-Brachial Index (less than 0.90) or pulse abolition, claudication, limb ischemia and/or non-traumatic amputation

Time Frame: Day 1

Percentage of participants (Y/N).

Diagnosed with symptomatic heart failure: New York Heart Association Functional Classification (NYHA) (group IIIV) and/or left ventricular ejection fraction (LVEF) greater than or equal to 50 percent, LVEF 40-49 percent and LVEF less than 40 percent)

Time Frame: Day 1

Percentage of participants (Y/N).

Diagnosed with asymptomatic heart failure

Time Frame: Day 1

Percentage of participants (Y/N).

Diagnosed with aortic diseases: Aortic dissection, aortic aneurysms and/or thromboembolic aortic disease

Time Frame: Day 1

Percentage of participants (Y/N).

Diagnosed with CVD: Myocardial infarction, stable coronary artery disease (SCAD) also referred as angina (pectoris), other ischaemic heart disease and/or past revascularisation procedures

Time Frame: Day 1

Percentage of participants (Y/N).

Diagnosed with carotid artery disease

Time Frame: Day 1

Percentage of participants (Y/N).

Diagnosed with cardiac arrhythmia: Atrial fibrillation or flutter, ventricular tachycardia and/or ventricular fibrillation

Time Frame: Day 1

Percentage of participants (Y/N).

Diagnosed with cerebrovascular disease: Ischaemic stroke, haemorrhagic stroke, stroke (unspecified) and/or transient ischaemic attack

Time Frame: Day 1

Percentage of participants (Y/N).

Hospitalisation for heart failure

Time Frame: Day 1

Percentage of participants (Y/N).

Secondary Outcomes

  • High risk of CVD (above 20% over 10 years) according to the risk engine from the United Kingdom Prospective Diabetes Study (UKPDS)(Day 1)

Study Sites (1)

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