Comparative Effects of Sensorimotor Interventions on Hand Motor Function and Performance in Patients With Stroke
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- Moberg Pick-up Test (MPUT)
研究概览
简要总结
This randomized controlled trial investigated the comparative effects of sensory, motor, and combined sensorimotor interventions on hand motor function and behavioral performance in patients with stroke. The study focused on upper-extremity impairments, particularly deficits in hand strength, dexterity, and reaction time, which are common following stroke and substantially limit functional independence. Sensorimotor integration plays a critical role in motor recovery, as effective hand function depends on the interaction between sensory feedback and motor control mechanisms.
Participants with stroke were randomly assigned to sensory, motor, or combined sensorimotor intervention groups. The interventions were designed to target tactile perception, motor coordination, and integrated sensorimotor processing through attended active and passive stimulation approaches. Outcome measures included hand grip strength, manual dexterity, and reaction time, which were evaluated before and after the intervention period.
The findings demonstrated that sensorimotor-based rehabilitation approaches positively influenced upper-extremity motor performance and behavioral responses in stroke patients. In particular, combined sensorimotor interventions appeared to provide more comprehensive improvements by simultaneously enhancing sensory processing and motor execution. These results support the importance of integrating sensory-focused strategies into conventional motor rehabilitation programs to optimize neuroplasticity and functional recovery after stroke. The study contributes to the growing evidence supporting multidimensional rehabilitation approaches for improving hand function and sensorimotor performance in individuals with stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 45 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having the ability to verbally communicate to answer questions
- •Willingness to participate in the study
- •Having read and signed the informed consent form
排除标准
- •Having joint movement restriction in the upper extremity
- •Presence of skin injury or scarring on the hand or wrist
- •History of surgery on the upper extremity
- •Having an orthopedic problem in the upper extremity
- •Having a rheumatic disease
- •Having a neurological condition in the upper extremity
- •Having a severe mental or cognitive impairment
研究组 & 干预措施
Sensory Exercise Group
干预措施: The Sensory Exercise Group (Other)
Motor Exercise Group
干预措施: The Motor Exercise Group (Other)
Combined Sensory and Motor Exercise Group
干预措施: Sensory and Motor Exercise Group (Other)
Control
The control group did not receive any additional treatments during the study period, allowing for a clear comparison between the experimental group and the baseline conditions.
结局指标
主要结局
Moberg Pick-up Test (MPUT)
时间窗: immediately after the intervention
Hand function was evaluated using the Moberg Pick-up Test (MPUT), a standardized method for assessing functional hand use and fine-motor skills, specifically measuring the ability to grasp and manipulate small objects. During the test, participants were instructed to pick up various small objects (e.g., coins and small blocks) and place them in a container as quickly as possible. During the test, the participants were instructed to pick up various small objects and place them in a container as quickly as possible. The assessment was conducted with the dominant hand, first with eyes open and then with eyes closed, to test sensory function. For each condition, the test was repeated three times, and the best performance time, recorded in seconds, was used for analysis. The objects used in the test were of similar size and required coordinated hand movements for successful completion, ensuring consistency in task difficulty
Muscle Reaction Time
时间窗: immediately after the intervention
Light Trainer® system, which consists of a wireless lighting system with LED pods and a central controller. The participants were seated with their hands on the table, 40 cm apart, palms down, and elbows at 90°. The Light Trainer was positioned centrally 20 cm away from each hand. When the pod was illuminated, the participants were instructed to turn off the light as quickly as possible by touching it. Light activation was randomized to avoid predictability, requiring participants to respond based on light cues each time. In the first task, the participants used their dominant hand to turn off the light as quickly as possible. In the second task, they responded to a light signal by deactivating a predetermined light from two different colors using their dominant hand. Scale Range: No minimum or maximum value in milliseconds (lower time is better). Interpretation: Lower reaction times signify better outcomes, as they reflect faster muscle response to visual stimuli.
Grip Strength (Measured Using Jamar Electronic Dynamometer)
时间窗: immediately after the intervention
Hand performance was assessed based on grip strength using a Takei Handheld Dynamometer (Takei Scientific Instruments Co., Tokyo, Japan). Participants were seated with elbows flexed at 90 degrees and forearms in a neutral position, and were instructed to squeeze the dynamometer with maximum force for 3-5 seconds, with the palm facing upwards. Each hand was tested three times with a 20-second rest between trials, and the highest value was recorded. This protocol ensures standardized and consistent results, with measurements documented in kilograms (kg) to provide reliable grip strength assessment. Scale Range: The dynamometer measures from 0 to 90 kg. Interpretation: Higher scores reflect stronger grip strength, which is indicative of better hand function.
次要结局
未报告次要终点
研究者
Gamze Demircioğlu
PhD
Atlas University