Effect of Elliptical Training on Metabolic Homeostasis in Metabolic Syndrome
- Conditions
- Metabolic Syndrome
- Interventions
- Behavioral: exercise training on elliptical deviceBehavioral: group B (control group)
- Registration Number
- NCT04635202
- Lead Sponsor
- Cairo University
- Brief Summary
The growing prevalence of metabolic syndrome (MetS) in the worldwide is becoming a serious health problem and economic burden. MetS has become a crucial risk factor for the development of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD). The rising rates of CVD and diabetes, which are the two leading causes of death. To prevent the progression of MetS to diabetes and CVD, regular physical activity is required.
Elliptical trainer device is a relatively new modality of exercise and is advertised to be superior to a treadmill because of the low joint impact and the more reasonable costs of an elliptical trainer compared to a treadmill. Additional quantitative research is needed to further evaluate the effectiveness of elliptical trainers and the physiological and perceptual responses to the machine.
- Detailed Description
Forty sedentary MeTS patients (from both sexes) will be randomly divided to group A and group B.
-Group A (Elliptical training group): This group (n=20) will receive aerobic training on an elliptical trainer for 16 weeks (3 sessions per week). The session will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR.
Group B: this group will continue their normal daily physical activities without any additional training
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
- The MeTS subjects who will have three or more of the following criteria: 1) waist circumference more than 102 cm, triglycerides more than 150 mg/dL, 3) blood pressure (BP) more than 130/85 mmHg, 4) high-density lipoprotein (HDL) less than 40 mg/dL, .
Exclusion criteria:
- Renal, pulmonary, cardiac, vascular, respiratory, hepatic, autoimmune disorders.
- Smoker, addictive, cancer, and alcoholic patients.
- Lower limb arthritis or any orthopaedic problem will hinder the training.
- Participation in any type of sport training in the previous 6 months.
- Pregnant or lactating women.
- Patients with thyroid gland dysfunction.
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description group A exercise training on elliptical device patients (n=30) in this group will receive 16 weeks of elliptical training on elliptical trainer, 3 times per week. the training will start with 5 minutes warming up at 50 % of maximal heart rate (MHR), 20-minute continuous ET at 70% of MHR, 12 minutes (4×3) intervals at 90% of MHR with a 3-minute active recovery at 70% of MHR between intervals, and finally 5-minute cool-down period at 50% of MHR Group B (control group) group B (control group) patients (n=30) in this group will receive general advises on maintaining physical activities
- Primary Outcome Measures
Name Time Method Triglycerides It will be measured after 16 weeks of training Triglycerides is one of lipid profile indicators
high density lipoprotein It will be measured after 16 weeks of training high density lipoprotein is one of lipid profile indicators
- Secondary Outcome Measures
Name Time Method Fasting blood glucose It will be measured after 16 weeks of training It will be measured via a blood glucose meter
Insulin It will be measured after 16 weeks of training it will be measured via a blood sample
The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance It will be measured after 16 weeks of training HOMA-IR = \[fasting insulin (μU/mL)
× fasting glucose (mmol)\]/22.5Waist circumference It will be measured after 16 weeks of training it will be measured by inelastic tape at the umbilicus level
weight It will be measured after 16 weeks of training the weight scale will be used
Leg strength test It will be measured after 16 weeks of training will be assessd by leg dynamometer
Systolic blood pressure It will be measured after 16 weeks of training It will be measured via Sphygmomanometer
diastolic blood pressure It will be measured after 16 weeks of training It will be measured via Sphygmomanometer
% body fat It will be measured after 16 weeks of training percentage of body fat composition
Trial Locations
- Locations (1)
Faculty of Physical Therapy Cairo University
🇪🇬Giza, Dokki, Egypt