NL-OMON47274
Completed
Not Applicable
Dopaminergic Functioning in Autism Spectrum Disorder - Dopaminergic Functioning in Autism Spectrum Disorder
Stichting Rivierduinen0 sites69 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Autism
- Sponsor
- Stichting Rivierduinen
- Enrollment
- 69
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. DSM\-5 diagnosis of Autism Spectrum Disorder (Patients only, for controls this is an exclusion criterion, see below).
- •2\. Age: 18\-30 years.
Exclusion Criteria
- •1\. DSM\-5 diagnosis of Autism Spectrum Disorder (Healthy controls only)
- •2\. Autism Spectrum Disorder due to a known organic disorder (\*Syndromal ASD\*, e.g., due to Fragile X syndrome, Klinefelter syndrome, 22q11 deletion syndrome).
- •3\. Neurological disorder (e.g., epilepsy) or evidence of brain damage.
- •4\. History of meningitis.
- •5\. Intellectual disability (IQ\<85\).
- •6\. Non\-affective Psychotic Disorder or Bipolar Disorder (DSM\-5: 297\.1, 298\.8, 295\.40, 295\.90, 295\.70, 292\.9, 291\.9, 293\.81, 293\.82, 293\.89, 298\.9, 296\.89, 303\.13, 293\.83, 296\.89, 296\.80, 296\.4x, 296\.5x, 296\.7\).
- •7\. Social exclusion due to other causes than ASD: visible ethnic minority status, serious physical disability, serious visual or hearing impairment; at discretion of the researcher.
- •8\. Current use of drugs (XTC, cocaine, etc.). Use of cannabis is allowed, but should have been stopped at least one month before the study. Cannabis abuse earlier in life is not allowed.
- •9\. Alcohol\- or drug abuse or dependence (DSM\-5\).
- •10\. Use of an antipsychotic (ever) if prescribed for a psychotic disorder, as a former psychotic disorder is an exclusion criterion. Occasionally, antipsychotics are prescribed against e.g. anxiety or aggression. In these cases:
Outcomes
Primary Outcomes
Not specified
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