Licorice Versus Standard Preventive Measures for the Prevention of Caries Incidence in Young Egyptian Adults: Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 81
- 试验地点
- 2
- 主要终点
- Incidence of new carious lesions
研究概览
简要总结
The objective is to conduct an RCT to evaluate the effectiveness of Licorice in comparison to standard caries preventive measures for the prevention of new carious lesions in high caries risk patients.
详细描述
Research hypothesis (Null hypothesis):
The present clinical trial will be conducted to reject or accept the null hypothesis that using Licorice extract mouth wash in addition to standard preventive measures will not differ from using standard preventive measures alone in preventing incidence of new carious lesions.
PICOTS:
P: Population with high caries risk patients
I: Use of licorice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with high caries risk,
- •18-25 years,
- •Males or females,
- •Medically free patients,
- •Patients approving to participate in the study.
排除标准
- •Patients who were on antibiotic therapy or corticosteroid therapy for 30 days before the examination,
- •Patients had history of professional cleaning in the last 15 days,
- •Patients with exposed pulp,
- •Evidence of parafunctional habits,
- •Patients with developmental dental anomalies,
- •Patients undergoing or will start orthodontic treatment,
- •Patients with removable prosthesis,
- •Periapical Abscess or Fistula.
结局指标
主要结局
Incidence of new carious lesions
时间窗: 12 months
Appearance of new carious lesions within the study duration
次要结局
未报告次要终点
研究者
Sara Mohammed Ahmed Mady
Principal Investigator
Cairo University