Efficacy of Licorice on Reducing Salivary Streptococcus Mutans Versus Chlorohexidine in Caries Risk Patients
Not Applicable
- Conditions
- Caries, Dental
- Interventions
- Other: licorice extract mouthwashOther: chlorohexidine mouthwash
- Registration Number
- NCT03590977
- Lead Sponsor
- Cairo University
- Brief Summary
To compare the effect of a natural herbal licorice containing preventive measure alternative to chlorohexidine preventive measure to decrease the effect of streptococcus mutans.
- Detailed Description
A total number of fifty-two patients will be enrolled in the study. They will be divided into two groups: study group and control group. Study group will be subjected to licorice mouthwash and the control will be subjected to chlorohexidine mouth wash. Salivary bacterial count will be evaluated for both groups.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
- over 18 years old
- co-operative patients
- not allergic to licorice
- not allergic to chlorohexidine
Read More
Exclusion Criteria
- pregnancy
- allergic patients to licorice
- allergic patients to chlorohexidine
- lack of compliance
- evidence of parafunctional habits
- patients with periodontal disease
- xerostomia
- participants that receive any microbial agent two weeks prior to the study
Read More
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description licorice extract mouthwash licorice extract mouthwash administration of a mouthwash containing licorice as a preventive measure to high caries risk patients (faculty of pharmacy, cairo university) chlorohexidine mouthwash chlorohexidine mouthwash administration of chlorohexidine 0.2% in 1:1 diluation mouthwash that is broad spectrum antimicrobial activity to high caries risk patients
- Primary Outcome Measures
Name Time Method salivary bacterial count after one week streotococcus mutans bacterial count
- Secondary Outcome Measures
Name Time Method