Evaluation the Efficacy of a Herbal Licorice on Reducing Salivary Streptococcus Mutans Levels (A Randomized Clinical Trial)
试验速览
- 阶段
- 不适用
- 入组人数
- 52
- 主要终点
- salivary bacterial count
研究概览
简要总结
To compare the effect of a natural herbal licorice containing preventive measure alternative to chlorohexidine preventive measure to decrease the effect of streptococcus mutans.
详细描述
A total number of fifty-two patients will be enrolled in the study. They will be divided into two groups: study group and control group. Study group will be subjected to licorice mouthwash and the control will be subjected to chlorohexidine mouth wash. Salivary bacterial count will be evaluated for both groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •over 18 years old
- •co-operative patients
- •not allergic to licorice
- •not allergic to chlorohexidine
排除标准
- •pregnancy
- •allergic patients to licorice
- •allergic patients to chlorohexidine
- •lack of compliance
- •evidence of parafunctional habits
- •patients with periodontal disease
- •xerostomia
- •participants that receive any microbial agent two weeks prior to the study
研究组 & 干预措施
licorice extract mouthwash
administration of a mouthwash containing licorice as a preventive measure to high caries risk patients (faculty of pharmacy, cairo university)
干预措施: licorice extract mouthwash (Other)
chlorohexidine mouthwash
administration of chlorohexidine 0.2% in 1:1 diluation mouthwash that is broad spectrum antimicrobial activity to high caries risk patients
干预措施: chlorohexidine mouthwash (Other)
结局指标
主要结局
salivary bacterial count
时间窗: after one week
streotococcus mutans bacterial count
次要结局
未报告次要终点
研究者
Nancy Helmy Blamon Mikhael
Assistant lecturer
Cairo University