Effect of Hydralazine on duration of soft tissue local anesthesia following dental treatment
- Conditions
- The effectiveness of Hydralazine HCl on the adverse effect of local anesthesia.Local anaesthetics
- Registration Number
- IRCT201312202877N2
- Lead Sponsor
- Vice Chancellor for Research of Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria:
Male or female greater than or equal to 18 years; Sufficiently healthy, as determined by the Investigator, to receive routine dental care; Requires one or two cartridges of local anesthesia administered by inferior alveolar nerve block techniques; Understands and gives written informed consent; Can communicate with the Investigator and study staff, and can understand and comply with the requirements of the protocol
History or presence of any condition that contraindicates routine dental care; Concurrent conditions: any incapacitating medical condition (e.g. unstable angina, uncontrolled cardiac arrhythmias, uncontrolled hypertension, uncontrolled hyperthyroidism); significant infection or inflammatory process of the oral cavity; Concomitant medications: use of an opioid or opioid-like analgesic (e.g. codeine, tramadol, pentazocine) within 48 hours prior to administration of anesthetic; Allergy or intolerance to lidocaine, articaine, prilocaine, mepivacaine, epinephrine, levonordefrin, sulfites, phentolamine, or topical benzocaine; Any condition which, in the opinion of the Investigator, increases the risk to the subject of participating in this study or decreases the likelihood of compliance with the protocol
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Soft tissue local anesthesia. Timepoint: Just one day. Method of measurement: ?Questionnaire.
- Secondary Outcome Measures
Name Time Method