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Clinical Trials/CTRI/2025/09/094814
CTRI/2025/09/094814
Completed
Post Marketing Surveillance

A Cross Sectional Study Comparing the Effects of Sevoflurane and Desflurane in adults patients undergoing General Anesthesia with Laryngeal Mask Airway

Department of Anesthesiology1 site in 1 country60 target enrollmentStarted: September 15, 2025Last updated:

Overview

Phase
Post Marketing Surveillance
Status
Completed
Enrollment
60
Locations
1
Primary Endpoint
To observe and compare group A and B regarding the total volume of the inhalational agent, namely Sevoflurane or Desflurane used, total dose of the analgesic drug requirement, intraoperative hemodynamic stability, oxygen saturation, postoperative recovery score, and postoperative side effects, if any, will be assessed and documented for comparison

Overview

Brief Summary

This research aims to evaluate and compare the clinical performance of two inhalational anaesthetic agents—sevoflurane and desflurane, in adult patients scheduled for elective surgical procedures under general anaesthesia (GA) using a laryngeal mask airway (LMA). The study will assess key perioperative parameters, including the duration of surgery, intraoperative Oxygen saturation, Haemodynamic stability based on heart rate, blood pressure, mean arterial pressure and postoperative recovery characteristics based on recovery score and side effects such as nausea, vomiting and delirium.

The goal is to determine which agent offers superior outcomes in terms of anaesthetic efficiency, patient safety, and recovery quality.

Study Design

Study Type
Pms
Allocation
Na
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • ASA physical status I and II Patients scheduled for elective surgery under GA with LMA Patient is willing to participate in the research.

Exclusion Criteria

  • ASA physical status III and above Pregnant patients, paediatric patients Patient scheduled for emergency surgeries Patient with a history of smoking, chronic alcoholism, drug abuse, and psychiatric disorder Patient refusal.

Outcomes

Primary Outcomes

To observe and compare group A and B regarding the total volume of the inhalational agent, namely Sevoflurane or Desflurane used, total dose of the analgesic drug requirement, intraoperative hemodynamic stability, oxygen saturation, postoperative recovery score, and postoperative side effects, if any, will be assessed and documented for comparison

Time Frame: Before starting the procedure, the baseline parameters of vital signs, SpO2, Heart rate, blood pressure, ECG, and temperature will be assessed. After every 10 minutes till the end of the surgery duration of surgery post post-operative recovery score, and once the patient recovers from General anaesthesia, all these parameters will be assessed and compared between the two groups

Secondary Outcomes

  • Nausea, Vomiting, Sore throat(Hourly for 4hrs then after 24hrs)

Investigators

Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

Ms A Jayaprabha

BIHER university

Study Sites (1)

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