The inhibitory effect of local anaesthetics on the G-protein-mediated vascular flare response to bradykinin and substance P

• Conditions: Healthy volunteers

• Registration Number: EUCTR2004-000333-10-GB
• Lead Sponsor: Research & Innovation Services, University of Dundee

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-02-17
• Last Update Posted: 24 June 2013

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Male
• Target Recruitment: 20

Inclusion Criteria

Healthy, male.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
;
Healthy, male.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Smokers, currently receiving medication, known hypersensitivity to amide local anaesthetics, history of vascular disease, history of hypersensitive responses such as hay fever and asthma.
;
Smokers, currently receiving medication, known hypersensitivity to amide local anaesthetics, history of vascular disease, history of hypersensitive responses such as hay fever and asthma.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified