JPRN-UMIN000013382已完成未知
Effect of co-administration of HMG-CoA Reductase Inhibitor on the endothelial dysfunction after continuous treatment of nitroglycerin in Japanese volunteers with aldehyde dehydrogenase2 Glu487Lys genotypes: randomized crossover trial - Effect of HMG-CoA Reductase Inhibitor on the endothelial dysfunction in Japanese volunteers with ALDH2 mutation
Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu Univertisy0 个研究点目标入组 44 人开始时间: 2014年3月11日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 44
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 40years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. History of cardiovascular disease 2. Severe hepatic dysfunction 3. Severe renal dysfunction 4. Woman who is pregnant or possibly be pregnant 5. History of severe allergy or allergic reaction to the drugs which are used in the present study 6. History of heart disease, glaucoma, peptic ulcer and aspirin-induced asthma 7. On medical treatment (exclude NSAIDs and sleeping pills taken as needed) 8. On medical treatment of phosphodiesterase 5 9. Systolic blood pressure <90 mmHg 10. Body weight <40 kg or >90 kg 11. Not appropriate to this study by other reasons
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