临床试验/NCT03133637

NCT03133637已完成不适用

Effect of Ceftriaxone on Neonatal Jaundice

University of Rochester1 个研究点分布在 1 个国家目标入组 27 人开始时间: 2016年3月最近更新: 2021年4月6日

适应症

干预措施

试验速览

阶段: 不适用
状态: 已完成
发起方: University of Rochester
入组人数: 27
试验地点: 1
主要终点: change in bilirubin binding assays

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

Ceftriaxone is an antibiotic often used for the management of sepsis. Neonates commonly have jaundice during the first postnatal week. Ceftriaxone will be given as standard of care for sepsis and investigators will observe the effect on jaundice.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

年龄范围: 3 Days 至 7 Days（Child）
性别: All
接受健康志愿者: 否

入选标准

•Term infants with sepsis requiring IV antibiotics for more than 3 days and who has total serum bilirubin 6-12 mg/dL and resolving by day 4 of life.

排除标准

•Infants with asphyxia (Apgar score <3 at 5 minutes), chromosomal disorder, failed hearing test at baseline, family history of hearing loss, unconjugated hyperbilirubinemia requiring phototherapy, TORCH infection, craniofacial malformations, listeria monocytogenes infection, and any clinical conditions which will preclude discharge to home.

研究组 & 干预措施

Ceftriaxone Arm

干预措施: ceftriaxone (Drug)

结局指标

主要结局

change in bilirubin binding assays

时间窗: baseline and through study completion, an average of 1 hour

次要结局

Automated brain stem evoke response test(through study completion, an average of 1 hour)

研究者

发起方

University of Rochester

申办方类型

Other

责任方

Sponsor

研究点 (1)

Loading locations...

相似试验

撤回

不适用

CEFTRIAXONE NEONATAL THERAPY (CEFSINT) : A RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE EFFECT OF CEFTRIAXONE ON HYPERBILIRUBINEMIAhyperbilirubinaemiajaundice10019654

NL-OMON37438Sint Elisabeth Ziekenhuis150

进行中（未招募）

1 期

CEFTRIAXONE NEONATAL THERAPY: A RANDOMIZED CONTROLLED TRIAL TO EVALUATE THE EFFECT OF CEFTRIAXONE ON HYPERBILIRUBINEMIAHyperbilirubinemia

EUCTR2011-004417-16-NLSt. Elisabeth Hospital

已完成

4 期

Infant Severe Sepsis and Bacterial Meningitis in MalawiInfant Bacterial Meningitis

NCT01247909Kamuzu University of Health Sciences351

已完成

2 期

Effects of intravenous ceftriaxone in neurologic outcome of acute spinalcord injury patients compared with methylprednixolone aloneSpinal Injury.Other injury of lumbar spinal cord?S34.1

IRCT2016102713947N5Road traffic injury prevention research center, Tabriz University of Medical Sciences60

Unknown

4 期

Pharmacokinetic of Ceftriaxone in Septic ICU PatientsSevere SepsisSepsisSeptic Shock

NCT00449800Association Pour La Promotion A Tours De La Reanimation Medicale70