Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment

Recruiting

• Conditions: Cognitive Impairment; Obstructive Sleep Apnea

• Registration Number: NCT04658290
• Lead Sponsor: Chinese University of Hong Kong

Brief Summary

The study is aimed to carry out an epidemiology study investigating the prevalence of obstructive sleep apnea (OSA) and the association with cognitive impairment.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-08-29
• Study First Submitted: 2020-08-31
• Study First Submitted QC: 2020-12-06
• Study First Posted: 2020-12-08
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-18
• Last Update Posted: 2024-02-20
• Primary Completion: 2026-08-28
• Study Completion: 2026-08-28

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Have stability of at least 4 weeks on permitted medications (i.e. medications known not to affect sleep architecture or circadian rhythms).

Exclusion Criteria

• Suspected dementia or a score of <24 on the mini-mental state examination
• A diagnosis of neurological disorders (e.g. Parkinson's Disease, Epilepsy, Multiple Sclerosis)
• Psychiatric disorders including current major depression; bipolar disorder; schizophrenia
• Other known clinically significant sleep disorders (e.g. narcolepsy)
• Been currently receiving CPAP or bi-level pressure for OSA

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Number of subjects having apnea-hypopnea index of more than 5	1 year

Secondary Outcome Measures

Name	Time	Method
incidence of cerebrovascular disease	5 years
Montreal Cognitive Assessment	5 years

Trial Locations

Locations (1)

Chinese University of Hong; 🇭🇰 Hong Kong, Please Select, Hong Kong