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临床试验/NCT02325258
NCT02325258已完成不适用

Assessment of a Proposed Microbiological Alert and Its Impact on a Sepsis Campaign

Emilio Bouza1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2012年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
300
试验地点
1
主要终点
Sepsis recognition in patients who had blood cultures drawn

研究概览

简要总结

The aim of the present study was to evaluate the ability of health-care professionals in addressing sepsis, and the impact of a telephone call upon receival of blood cultures in the clinical microbiology department, from a clinical microbiologist, in the early management of sepsis.

详细描述

Sepsis is one of the major challenges of modern medicine. It is an important health problem with a high incidence, morbidity and mortality that affects population worldwide. Without an early recognition and a prompt management, patients can develop more severe stages of the disease and even death. An appropriate and aggressive management can significantly improve outcomes. Thus, it is necessary to develop early warning systems of sepsis in the hospital.

In recent years, several campaigns and guidelines have been developed to help health care professionals in the management of sepsis. However, these have mainly focused on management protocols for severe sepsis and septic shock in intensive care units or emergency departments. To the best of the investigators knowledge, none of these have examined in depth either the impact of a sepsis alert system in general wards, nor the impact of a telephone call from a specialist in Clinical Microbiology, upon blood culture request, in the early recognition of sepsis.

The aim of the present study was to evaluate the ability of health-care professionals in addressing sepsis, and the impact of a telephone call upon receival of blood cultures in the clinical microbiology department, from a clinical microbiologist, in the early management of sepsis.

For this, the investigators performed a prospective study based on telephone calls followed by a phone interview to physicians and nurses in charge of patients whose blood cultures had just been received at the clinical microbiology department in a tertiary hospital.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •In-patients with blood cultures drawn and sent to the Microbiology laboratory, regardless of patient allocation (eg., emergency department, intensive care units, general wards)
  • •Opportunity sampling: patients whose clinical history number ended in odd numbers were assigned to group A (intervention) and patients whose clinical history number ended in even numbers were assigned to group B (no intervention, control group).
  • •Inclusion Criteria:
  • •Patients who had blood cultures drawn and sent to the Microbiology Laboratory, during the morning shift (from 9 am to 3 pm, Monday to Friday)
  • •Patients >/=18 years old

排除标准

  • •Patients <18 years old
  • •Patients with a recent bacteremic episode with no subsequent negative blood cultures
  • •In-patients with blood cultures drawn to whom the telephone call had already been performed.

研究组 & 干预措施

Telephone call

Experimental

Telephone call to physicians in charge of patients who have just had blood cultures drawn. Diagnostic and therapeutic recommendations to physicians in charge.

干预措施: Telephone call (Other)

No telephone call

No Intervention

control arm: no intervention

结局指标

主要结局

Sepsis recognition in patients who had blood cultures drawn

时间窗: 72 h

Use of diagnostic resources and antimicrobial consumption

次要结局

  • Health care professionals who correctly identify a case of sepsis(72 h)

研究者

发起方
Emilio Bouza
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Emilio Bouza

Head of Department

Hospital General Universitario Gregorio Marañon

研究点 (1)

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