To compare the efficacy and side effect profile of injectable and oral form of beta blocker drug propranolol in a type of vascular mass of the eye regio
- Conditions
- Health Condition 1: null- periorbital and eyelid capillary haemangioma
- Registration Number
- CTRI/2017/08/009440
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
1 Newly diagnosed cases of periorbital and eyelid capillary haemangiomas
2 Only those patients or whose guardians sign a written informed consent
3 No complications like ulceration/ necrosis
4 No previous intervention
5 No history of any systemic illness including asthma/ heart disease/ diabetes mellitus
6 No history of developmental delay
1 Patients not willing for treatment or follow up
2 Previously treated patients
3 Presence of systemic illnesses including recurrent breathing problem/ asthma; cardiac problems including AV block, CHF, sinus bradycardia; history of seizures; history of diabetes mellitus
-Abnormalities found in blood investigations
-Failure to get Cardiology Clearance for the intervention
-Additional ocular pathologies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method resolution of lesionTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method o change in size with continuous propranolol for 3 months <br/ ><br> <br/ ><br>Timepoint: 3 months;Obvious enlargement of lesion despite continuous treatment for 2 months <br/ ><br> <br/ ><br>Timepoint: <br/ ><br>2months;Partial regression followed by no response for 3 months <br/ ><br>Timepoint: 3 months