The Cognitive and spOrt Virtual EPIC Training Study: INVESTIGATING THE EFFECTS OF HOME-BASED EXERCISE AND COGNITIVE TRAINING
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 127
- 试验地点
- 2
- 主要终点
- Change in general cognitive functioning
研究概览
简要总结
The proposed COVEPIC trial is designed to document the effects of remote monitoring of physical exercise and home-based cognitive training on cognitive and physical functions in older adults.
详细描述
Due to the actual pandemic of COVID-19 around the world, social distancing is recommended, which causes a reduction of social interaction and physical activity. Therefore, this health crisis may have collateral effects on cognitive, physical, and psychological health, especially in elderly people who are more likely to be isolated, and for whom social distancing is of paramount importance. Physical exercise practice has been demonstrated to improve cognitive functioning, along with mobility and physical capacity, and to promote psychological well-being. This is the reason why governmental health authorities, as well as the scientific community recommend to stay physically active, especially in this pandemic period. However, in the current context full-time physical training in sport centres cannot be largely promoted. Effective solutions to help older adults in maintaining regular and efficient physical exercise while maintaining social distancing, are thus needed. Consequently, the current project proposes first to investigate the potential of a remote monitoring of physical activity to promote cognitive, physical and psychological health of older adults. Also, considering the added benefits of combining cognitive training to physical exercise to further enhance health and cognition in seniors, this project also addresses the added benefits of a multidomain intervention combining a physical exercise intervention with a home-based cognitive training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
盲法说明
This clinical trial is a single-blinded study. Research personnel performing the outcome assessments at baseline, three, six and twelve months will be blinded to group allocation. Participants will be aware of the type of training they receive.
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult aged 50 and older
- •Have access to internet
- •Have access to a tablet (i.e. iPad or Android) or a computer
排除标准
- •Non-cardiopulmonary limitation to exercise (e.g., arthritis)
- •Severe exercise intolerance
- •Respiratory disease (e.g., asthma, COPD, COVID-19)
- •Mini Mental Scale Examination (MMSE) telephone version lower than 19/23
- •Diagnostic of cardiovascular disease (e.g., chronic systolic and diastolic heart failure, somatic aortic stenosis, atrial fibrillation, malignant arrhythmias, documented atherosclerotic disease).
结局指标
主要结局
Change in general cognitive functioning
时间窗: Baseline and post-intervention at 6 months.
Validated remote version of Montreal Cognitive Assessment (0-28 score, with a higher score indicating a better cognitive functioning).
Change in executive functions
时间窗: Baseline and post-intervention at 6 months.
Validated remote version of neuropsychological tests and iPad tests (Composite Z-score).
Change in episodic memory
时间窗: Baseline and post-intervention at 6 months.
Validated remote version of neuropsychological tests and iPad tests (Composite Z-score).
Change in processing speed
时间窗: Baseline and post-intervention at 6 months.
Validated remote version of neuropsychological tests and iPad tests (Composite Z-score).
次要结局
- Change in Cardiorespiratory fitness(Baseline and post-intervention at 6 months.)
- Change in Walking speed(Baseline and post-intervention at 6 months.)
- Change in Functional mobility(Baseline and post-intervention at 6 months.)
- Change in Balance performance(Baseline and post-intervention at 6 months.)
- Change in Lower limb muscles strength(Baseline and post-intervention at 6 months.)
研究者
Louis Bherer
Associate scientific director, Direction of prevention, Montreal Heart Institute
Montreal Heart Institute