Diagnostic performance of MSCT in cardiomyopathy patients

Recruiting

• Conditions: coronary atherosclerosis; 10011082

• Registration Number: NL-OMON30959
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 60

Inclusion Criteria

- patient is symptomatic
- LVEF <45% and/ or FS<25% as measured by echocardiography.
- and/ or dilation on echo of left ventricle (male >60 mm./ female >55 mm.).
- cardiomyopathy of unknown origin (ischemic/non-ischemic).
- willing to participate.
- signed a written consent form approved by the ethical committee of Erasmus MC.
- MSCT possible within two months before invasive angiography.

Exclusion Criteria

- intolerance for Iodine.
- creatinine level >120.
- coronary stent placement or bypass grafting in the past.
- known myocardial infarction
- pregnancy
- not being able to breath hold for 15 seconds.
- under the age of twenty
- being incapacitated
- acute patients

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Diagnostic performance of MSCT will be demonstrated in terms of specificity,<br /><br>sensitivity, PPV, NPV and accuracy. ICA will be used as the standard of<br /><br>reference. For the MSCT a combination of calcium scoring (first) and coronary<br /><br>angiography (second) will be performed.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>NA</p><br>