Does A Single Low Dose Preoperative Intravenous Erythropoietin Affect Postoperative Blood Loss and Transfusion in Elderly Hip Fracture Patients Receiving Intravenous Iron Therapy: A Prospective Triple-Blinded Randomized Controlled Trial

Phase 1

Completed

• Conditions: Hip fracture; Recombinant human erythropoietin; Elderly hip fracture; Allogeneic blood transfusion; Postoperative Blood Loss

• Registration Number: TCTR20180606005
• Lead Sponsor: Ramathibodi hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-12-31
• Study Start: 2018-06-06
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

1) aged over 60 years
2) having low-energy trauma
3) having no contraindication for hip fracture surgery
4) willing to participate into this study

Exclusion Criteria

1) delayed presentation more than 5 days after having injury
2) having myeloproliferative disorder
3) having uncontrolled hypertension
4) having serum creatinine > 2.0 mg/dL
5) having coagulopathy or taking anticoagulant therapy
6) having hemochromatosis
7) having inflammatory arthritis
8) allergic to rHuEPO or intravenous iron sucrose

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Total hemoglobin loss day 3 Preop hemoglobin+total blood in-postop hemoglobin

Secondary Outcome Measures

Name	Time	Method
Total hemoglobin loss 2 weeks Preop hemoglobin+total blood in-postop hemoglobin,blood transfusion rate 3 days unit of blood component