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临床试验/NCT02995798
NCT02995798已完成不适用

The Characteristics of Regional Bone Quality in the Cervical Vertebrae Considering BMD

Gangneung Asan Hospital1 个研究点 分布在 1 个国家目标入组 99 人开始时间: 2009年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
99
试验地点
1
主要终点
Cortical bone Thickness

研究概览

简要总结

Data of CT images and the femoral neck BMD were obtained from 99 patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months) from April 2009 to December 2014. There were 52 females and 47 males. The mean age was 63.7 year (female: 63.4 years, male: 64.1; range 32-86 years). The patient was excluded who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass. Patients were divided into three groups according to femoral neck BMD (Group A, T-score ≥-1; Group B, -2.5<T-score<-1.0; Group C, T-score≤-2.5). Group A had normal BMD patients, Group B had lower normal patients including osteopenic patients and Group C presented osteoporotic patients. The mean HU numbers of cortical bone area in the vertebral canal (cHU, the medial wall of the lateral mass), the posterior wall of transverse foramen (fHU), the medial (mHU), lateral wall (lHU) and trabecular area of pedicle (pHU) were measured on the axial CT images in clinical images.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
25 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months)

排除标准

  • Who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass.

结局指标

主要结局

Cortical bone Thickness

时间窗: two weeks

HU number

时间窗: two weeks

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Moon-Kyu Kim, MD, Ph.D

Professor

Gangneung Asan Hospital

研究点 (1)

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