The Characteristics of Regional Bone Quality in the Cervical Vertebrae Considering BMD

Completed

• Conditions: Cortical Bone Thickness
• Interventions: Other: Cortical Bone thickness and Hounsfield unit (HU) numbers

• Registration Number: NCT02995798
• Lead Sponsor: Gangneung Asan Hospital

Brief Summary

Data of CT images and the femoral neck BMD were obtained from 99 patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months) from April 2009 to December 2014. There were 52 females and 47 males. The mean age was 63.7 year (female: 63.4 years, male: 64.1; range 32-86 years). The patient was excluded who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass. Patients were divided into three groups according to femoral neck BMD (Group A, T-score ≥-1; Group B, -2.5\<T-score\<-1.0; Group C, T-score≤-2.5). Group A had normal BMD patients, Group B had lower normal patients including osteopenic patients and Group C presented osteoporotic patients. The mean HU numbers of cortical bone area in the vertebral canal (cHU, the medial wall of the lateral mass), the posterior wall of transverse foramen (fHU), the medial (mHU), lateral wall (lHU) and trabecular area of pedicle (pHU) were measured on the axial CT images in clinical images.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-04
• Primary Completion: 2014-12
• Study Completion: 2016-08
• Status Verified: 2016-12
• Study First Submitted: 2016-12-09
• Study First Submitted QC: 2016-12-14
• Last Update Submitted: 2016-12-14
• Study First Posted: 2016-12-16
• Last Update Posted: 2016-12-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 99

Inclusion Criteria

• Patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months)

Exclusion Criteria

• Who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group B	Cortical Bone thickness and Hounsfield unit (HU) numbers	-2.5\<T-score\<-1.0
Group A	Cortical Bone thickness and Hounsfield unit (HU) numbers	T-score ≥-1
Group C	Cortical Bone thickness and Hounsfield unit (HU) numbers	T-score≤-2.5

Primary Outcome Measures

Name	Time	Method
Cortical bone Thickness	two weeks
HU number	two weeks

Trial Locations

Locations (1)

Moon-Kyu Kim; 🇰🇷 Gangneung, Kangwondo, Korea, Republic of