Randomised trial of N-acetylcysteine in laparoscopic bariatric surgery

Not Applicable

Completed

• Conditions: Morbid obesity /non-alcoholic fatty liver disease; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN81349394
• Lead Sponsor: King's College Hospital NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-02-28
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

1. Male or Female
2. Aged 18 to 65
3. National Institute of Clinical Excellence criteria for morbid obesity surgery: BMI >40 or BMI >35 with obesity related complications

Exclusion Criteria

1. Pregnancy
2. History of chronic liver disease, including viral hepatitis, haemachromatosis, alcoholic liver disease or known alcohol intake >20g/day
3. Previous liver surgery, e.g., resection, orthotopic transplantation
4. Psychiatric illness, including anxiety, mood and eating disorders
5. Bleeding tendency or anticoagulant medications
6. Known allergies to N-acetylcysteine or related compounds

Study & Design

• Study Type: Interventional
• Study Design: Not specified