Effect of esketamine on hemodynamics of cesarean section under epidural anesthesia
- Conditions
- Incidence of hypotension during surgeryVAS scores during operation and 24 and 48 hours after operationIntraoperative and postoperative sedation scores 1h and 2h
- Registration Number
- ChiCTR2400088837
- Lead Sponsor
- Guiyang maternal and child health care hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- Not specified
(1)Single pregnancy full-term pregnancy cesarean section;<br>(2)American Society of Anesthesiologists (ASA) Grade I to II<br>(3)Women of childbearing age over 18 years old, gestational age is greater than or equal to 37 weeks<br>(4)BMI 18~40kg/m2;<br>(5)There are no contraindications to intraspinal anesthesia<br>(6)Volunteer for the study and obtain informed consent
exclusion criteria:(1)Known allergy to esketamine;(2) Persons with mental illness or cognitive impairment who are unable to perform relevant assessments;(3)Fetal distress or abnormality, placenta previa, placental abruption.<br>(1) After entering the operating room, the patient had two resting periods in the supine position with SBP>140 mmHg or SBP<90mmHg; (2) The amount of blood lost during the operation exceeds 15% of the total maternal blood volume; (3) The dural membrane was accidentally punctured, the catheter was placed in the blood vessel or the subarachnoid space; (4) Patients with poor epidural anesthesia effect who need to change the anesthesia program; (5) A serious condition has occurred that may require treatment; (6) Situations in which the investigator believes that termination of the study would be beneficial to the maternal health.<br><br><br>
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of hypotension during surgery;
- Secondary Outcome Measures
Name Time Method The score of VAS;sedation score;Neonatal Apgar score;