Effect of Mirtazapine on aggression in patients with Alzheimer
Phase 3
Recruiting
- Conditions
- Alzheimer's dementia.Alzheimer's disease
- Registration Number
- IRCT20210613051565N1
- Lead Sponsor
- niversity of social welfare and rehabilitation sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Adult patients (over the age of 18)
With Alzheimer's dementia
At least two years have passed since the onset of the disease
Confirm by a neurologist or psychiatrist with the NIA-AA (2011 National Institute on Aging and Alzheimer's Association) diagnostic criteria assistant.
Participant's consent
Cohen-Mansfield Agitation Inventory (CMAI) test score more than 45
Exclusion Criteria
No psychiatric disability
No physical disability
No neurological disability
Any disease with significant cognitive Impairment, (mental retardation)
No substance abuse in the previous six months
No extra psychiatric medication
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method -Cognitive changes by the MMSE - symptoms of agitation and aggression by the CMAI. Timepoint: In 0,4,6 weeks. Method of measurement: Questionnaire Mini–mental state examination(MMSE) ,Questionnaire Cohen Mansfield Agitation Inventory(CMAI).
- Secondary Outcome Measures
Name Time Method