NCT00576030终止不适用
Short-term Autonomic Effects of Caffeinated and Decaffeinated Espresso in Young Healthy Individuals
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 77
- 试验地点
- 1
- 主要终点
- Heart rate variability
研究概览
简要总结
More than 80% of the population in the USA consume coffee each day. However there not many studies on change of heart rate variability and placebo effects after consumption of coffee.
In our study we aim to test the following hypotheses:
- Habitual caffeinated espresso coffee drinkers show an increase in blood pressure, heart rate variability and parasympathetic activity (high frequency band) of the heart.
- Non-habitual caffeinated espresso coffee drinkers show an increase of blood pressure. The heart rate variability and the parasympathetic activity of the heart will decrease.
- Caffeinated or decaffeinated espresso induces comparable changes in habitual or non-habitual coffee drinkers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18- 50 years old, healthy
排除标准
- •Medication, obese(BMI > 30)
结局指标
主要结局
Heart rate variability
时间窗: 70 minutes
次要结局
- blood pressure(70 min.)
研究者
研究点 (1)
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