Identifying novel biomarkers in left ventricular hypertrophy patients
Withdrawn
- Conditions
- biomarkersheart hypertrophy10028593
- Registration Number
- NL-OMON32278
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
Patients are included in this study when planned for surgical aortic valve replacement for severe aortic valve stenosis. Signs of left ventricular hypertrophy have to be present either on ECG, echocardiography or MRI. None of the exclusion criteria are met. Written informed consent is obtained.
Exclusion Criteria
Patients with concomitant heart disease: previous myocardial infarction, endocarditis. Patients younger than 18 years of age are also excluded from participation in this study. Patients who have a syndromic or genetic diagnosis, for example, Marfan*s disease, trisomy 21, and Turner*s syndrome
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>identifying proteins involved in myocardial hypertrophy</p><br>
- Secondary Outcome Measures
Name Time Method <p>validation of biomarkers in hypertrophic myocardial tissue</p><br>