A study to predict the course of disease using alternative marker in patients with severe infectio
Not Applicable
- Conditions
- Health Condition 1: A419- Sepsis, unspecified organism
- Registration Number
- CTRI/2024/02/062479
- Lead Sponsor
- Dr Sanchit Mittal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1) Patients admitted with the diagnosis of Sepsis in Kasturba Hospital, Manipal under the Department of General medicine 2) quick sequential organ failure assessment score (qSOFA) of 2 or more in patients with presumed infection will be used to define sepsis
Exclusion Criteria
1) Lack of PT-INR or albumin data within 24 hours of diagnosis of sepsis.
2) Pregnant patients
3) Patients with Malignancy
4) Patients on Anti coagulation therapy
5) Liver transplantation
6) Renal diseases like Nephrotic and Nephritic syndrome
7) Obstructive jaundice
8) Patients who have received Albumin or undergone plasmapheresis
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To calculate the PT-INR to Albumin ratio in patients with sepsis and it’s prognostic efficiency in predicting patient outcome.Timepoint: At the time of discharge or death
- Secondary Outcome Measures
Name Time Method ?To compare the PT-INR to Albumin score with APACHE II score in predicting mortality in patients with sepsisTimepoint: At the time of discharge or death;?To correlate the PT-INR to Albumin ratio with requirement of Mechanical Ventilation, Hemodialysis and Inotropes.Timepoint: During the hospital stay of patient