Cyclophotocoagulation in Primary Open Angle Glaucoma

Not Applicable

• Conditions: Primary Open Angle Glaucoma
• Interventions: Procedure: Cyclophotocoagulation

• Registration Number: NCT04430296
• Lead Sponsor: Cairo University

Brief Summary

The use of Cyclodestruction procedures has been extended to patients with non-refractory glaucoma and good vision. Our aim is to compare the safety and efficacy of three cyclodestructive treatments; High Intensity Focused Ultrasound (HIFU) Cyclocoagulation versus micropulse cyclophotocoagulation (MP-CPC) versus transscleral continuous wave cyclophotocoagulation (CW-CPC) for the treatment of Primary open angle glaucoma.

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-06
• Study First Submitted: 2020-06-10
• Study First Submitted QC: 2020-06-10
• Last Update Submitted: 2020-06-10
• Study First Posted: 2020-06-12
• Last Update Posted: 2020-06-12
• Study Start: 2020-08-01
• Primary Completion: 2021-03-01
• Study Completion: 2021-08-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

• medically uncontrolled, primary open angle glaucoma attending glaucoma clinic

Exclusion Criteria

• patients with history of previous laser or surgical intervention

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Continuous Wave cyclophotocoagulation (CW-CPC)	Cyclophotocoagulation	-
MicroPulse cyclophotocoagulation (MP-CPC)	Cyclophotocoagulation	-
High Intensity Focused Ultrasound Cyclophotocoagulation (HIFU)	Cyclophotocoagulation	-

Primary Outcome Measures

Name	Time	Method
Success rate.	6 months	The success will be defined as IOP between 6 and 21 mmHg and at least a 30% reduction in IOP with or without topical IOP lowering medications.

Secondary Outcome Measures

Name	Time	Method
Frequency of complications	6 months