To compare the efficacy of hearing gain and functional success between cartilage and temporal fascia grafts in patients undergoing endoscopic type 1 tympanoplasty
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/07/071630
- Lead Sponsor
- Dr Rajendra Prasad Government Medical College Kangra At Tanda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
2.The patients requiring type 1 tympanoplasty.
3.Central perforation.
4.Intact ossicular chain on endoscopic examination.
5.Dry ear for more than 3 months.
6.No mastoid surgery in the past.
7.Minimum follow up of 1 year.
8.Patients with informed consent.
Exclusion Criteria
Affected/ distorted ossicular chain on endoscopic examination.
Total and marginal perforation.
Revision surgeries.
Cholesteatoma and retraction pockets.
Patients unwilling to participate in study.
Chronic sinusitis
allergic rhinitis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The tympanic membrane being intact without retraction or lateralization at 4weeks, 12 weeks and 24 weeks, and the difference between pre op and post op air bone gap (ABG) at 24 weeksTimepoint: 24 weeks
- Secondary Outcome Measures
Name Time Method ATimepoint: NA
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie cartilage graft integration in endoscopic tympanoplasty?
How does cartilage graft compare to temporal fascia in terms of hearing gain and functional outcomes in type 1 tympanoplasty?
Are there specific biomarkers that predict graft success in middle ear reconstruction surgeries?
What are the potential adverse events associated with cartilage grafts in endoscopic ear surgeries?
What are the current standard-of-care treatments for tympanic membrane perforations and how do they compare to cartilage grafts?