Evaluation of coronally advanced flap with Collagen Membrane (PERIOCOL) with or without Insulin Growth Factor-1 (1GF-1) for the treatment of maxillary anterior gingival recession defects: A Comparative Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Recession length and width measured (in mm) measured by UNC-15 periodontal probe and vernier caliper at baseline 1 month and 3 months
研究概览
简要总结
INTRODUCTION - Gingival recession is the apical migration of gingival edge to the junction of cementum and enamel (CEJ). periodontal disease, accumulations, inflammation, poor flossing, vigorous tooth brushing, erroneous occlusal connections, and dominating roots are all potential causes of gingival recession**. due to the exposed dentin, gingival recession may produce increased sensitivity.**
OBJECTIVE **–**The aim of the present study will be to comparatively evaluate the treatment of Miller class I and Class II recession defects with Coronally advanced flap along with GTR membrane and Insulin derived growth factor versus Coronally advanced flap with GTR membrane alone
METHODOLOGY –Twenty systemically healthy patients with a total of 20 gingival recession defects (Miller class I and class II) in teeth showing clinical evidence of recession defect will be selected for the study. 10 patients will be subjected to coronally advanced flap with collagen membrane and Insulin like growth factor 1 whereas 10 patients will be subjected to coronally advanced flap with collagen membrane .
RESULTS – On 3 months a gain in clinical attachment level , increase in width of keratinized gingiva and gain in root coverage will be observed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients should be free of systemic disease.
- •Miller’s Class I and II gingival recession defect at the buccal aspect of maxillary incisors or canines or premolars.
- •No previous periodontal surgery at the affected teeth.
- •Evidence of patient’s ability to perform good plaque control.
排除标准
- •Patient with history of any recent periodontal surgery in past 6 months.
- •Pregnant and lactating patients.
- •Recession defects associated with demineralization/caries, deep abrasion or restorations as well as teeth with evidence of pulpal pathology.
- •Un-cooperative patients.
结局指标
主要结局
Recession length and width measured (in mm) measured by UNC-15 periodontal probe and vernier caliper at baseline 1 month and 3 months
时间窗: Recession length and width measured (in mm) measured by UNC-15 periodontal probe and vernier caliper at baseline 1month and 3 months
次要结局
- Clinical attachment level (in mm) measured by UNC-15 periodontal probe(Baseline, 1 month, 3 months)
研究者
Dr Aman Narang
Subharti Dental College and Hospital