Dexamethasone as an adjuvant to ropivacaine in mandibular nerve block
Not Applicable
- Conditions
- Health Condition 1: null- Patients with ASA physical status classification I and II, belonging to the age group of 18â??65 years, with unilateral fracture mandible.
- Registration Number
- CTRI/2017/11/010559
- Lead Sponsor
- Department of Anaesthesiology Pain Medicine and Critical Care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Patients undergoing surgery for unilateral fracture mandible.
2. Patients belonging to the age group of 18â??65 years
3. Patients with ASA physical status classification I and II
Exclusion Criteria
1. Patient refusal to participate in the study.
2. Presence of any coagulopathy in the patient.
3. Presence of infection at the site of injection.
4. History of known allergy to any of the study drugs.
5. History of severe systemic diseases- Hepatic, Renal, Cardiac.
6. Presence of obesity with BMI more than 30 kg/m2.
7. Inability to comprehend pain assessment scales
8. Patients with failure of block.
9. Significant distortion in anatomy of block site.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to 1st request for analgesia (denoting duration of analgesia) after mandibular nerve block with a solution of dexamethasone (4mg) to 5ml of ropivacaine 7.5mg/ml when compared to 5ml of ropivacaine 7.5mg/ml and 1ml of 0.9% normal saline, prior to administration of GA in patients posted for mandibular surgeries.Timepoint: 0,1,2,4,6, 12,18 and 24 hours
- Secondary Outcome Measures
Name Time Method Reduction in postoperative pain scores in patients who receive mandibular nerve block with dexamethasone (4mg) and 5ml of ropivacaine 7.5mg/ml and with 5ml of ropivacaine 7.5mg/ml alone, prior to GA in patients undergoing mandibular surgeries. <br/ ><br>Timepoint: 24 hours;The total opioid consumption in 24hours period after surgery in patients who receive mandibular nerve block with dexamethasone (4mg) and 5ml of ropivacaine 7.5mg/ml and with 5ml of ropivacaine 7.5mg/ml alone, prior to GA in patients undergoing mandibular surgeriesTimepoint: 24 hours