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临床试验/PACTR202005626842621
PACTR202005626842621已完成2 期

Effect of moringa oleifera leaves on the blood glucose, blood pressure, lipid profile and haematological parameters of type 2 diabetics in a rural Nigerian community.

Ifeoma Christiana Afiaenyi0 个研究点目标入组 30 人开始时间: 2020年4月28日最近更新:
适应症

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
30

研究概览

简要总结

There was no significant (p > 0.05) difference in the waist circumference and waist hip ratio in all the groups after the feeding trial. There was no significant (p > 0.05) difference in the fasting blood glucose in all the groups after the feeding trial. Groups 3 (experimental group that consumed 40 g of Moringa oleifera leaves per day) and 4 (experimental group that consumed 60 g of Moringa oleifera leaves per day) had a significant (p < 0.05) decrease in their mean systolic pressure after the feeding trial. No significant (p > 0.05) difference was seen in the mean diastolic pressure and mean total cholesterol of the subjects after the feeding trial. There was a significant (p < 0.05) increase in the mean triglyceride level of the subjects in group 3. A significant (p < 0.05) reduction in low density lipoprotein was seen in group 2 (experimental group that consumed 20 g of Moringa oleifera per day) subjects. Group 3 subjects had significant (p < 0.05) increase in their mean very low density lipoprotein after the feeding trial. There was a significant (p < 0.05) increase in the mean high density lipoprotein in groups 1, 2 and 4. Significant (p < 0.05) reduction in the mean haemoglobin level, packed cell volume and white blood cell count was seen only in group 4 subjects. Significant changes observed in the parameters assessed were not dose dependent.

研究设计

研究类型
Interventional

入排标准

年龄范围
45 Year(s) 至 64 Year(s)(—)
性别
All

入选标准

  • Type 2 diabetics aged 40 years and above.
  • Type 2 diabetics with no obvious complications such as foot ulcer, blindness and stroke.
  • Type 2 diabetics who were neither pregnant nor breastfeeding.
  • Type 2 diabetics who were not obese.
  • Type 2 diabetics who consented to partake in the study.

排除标准

  • Type 2 diabetics who were below 40 years of age.
  • Type 2 diabetes with such complications such as foot ulcer, blindness and stroke.
  • Type 2 diabetics who were either pregnant or breastfeeding.
  • Type 2 diabetics who were obese.
  • Type 2 diabetics who did not give their consent to partake in the study.

研究者

发起方
Ifeoma Christiana Afiaenyi

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