Effect of moringa oleifera leaves on the blood glucose, blood pressure, lipid profile and haematological parameters of type 2 diabetics in a rural Nigerian community.
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 30
研究概览
简要总结
There was no significant (p > 0.05) difference in the waist circumference and waist hip ratio in all the groups after the feeding trial. There was no significant (p > 0.05) difference in the fasting blood glucose in all the groups after the feeding trial. Groups 3 (experimental group that consumed 40 g of Moringa oleifera leaves per day) and 4 (experimental group that consumed 60 g of Moringa oleifera leaves per day) had a significant (p < 0.05) decrease in their mean systolic pressure after the feeding trial. No significant (p > 0.05) difference was seen in the mean diastolic pressure and mean total cholesterol of the subjects after the feeding trial. There was a significant (p < 0.05) increase in the mean triglyceride level of the subjects in group 3. A significant (p < 0.05) reduction in low density lipoprotein was seen in group 2 (experimental group that consumed 20 g of Moringa oleifera per day) subjects. Group 3 subjects had significant (p < 0.05) increase in their mean very low density lipoprotein after the feeding trial. There was a significant (p < 0.05) increase in the mean high density lipoprotein in groups 1, 2 and 4. Significant (p < 0.05) reduction in the mean haemoglobin level, packed cell volume and white blood cell count was seen only in group 4 subjects. Significant changes observed in the parameters assessed were not dose dependent.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 45 Year(s) 至 64 Year(s)(—)
- 性别
- All
入选标准
- •Type 2 diabetics aged 40 years and above.
- •Type 2 diabetics with no obvious complications such as foot ulcer, blindness and stroke.
- •Type 2 diabetics who were neither pregnant nor breastfeeding.
- •Type 2 diabetics who were not obese.
- •Type 2 diabetics who consented to partake in the study.
排除标准
- •Type 2 diabetics who were below 40 years of age.
- •Type 2 diabetes with such complications such as foot ulcer, blindness and stroke.
- •Type 2 diabetics who were either pregnant or breastfeeding.
- •Type 2 diabetics who were obese.
- •Type 2 diabetics who did not give their consent to partake in the study.
