Comparison of intranasal and intravenous dexmedetomidine for prevention of post spinal shivering in patients undergoing lower limb orthopedic surgery

Not Applicable

• Conditions: Patients undergoing elective lower limb orthopedic surgeries under subarachnoid blockade were recruited into the study.

• Registration Number: JPRN-UMIN000042760
• Lead Sponsor: Department of Anaesthesiology, People's Hospital of Chongqing Banan District

Brief Summary

.A.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-12-28
• Study Completion: 2020-12-28
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Not provided

Exclusion Criteria

1, obese; 2, taking vasoactive or antidepressant drugs, receiving intraoperative blood or blood products transfusion; 3, with cardiac disease (heart blocks, bradyarrhythmias, and left ventricular failure), renal disease, hepatic disease, psychiatric disorder, neuropathies or severe diabetic autonomic neuropathy; 4, known history of substance or alcohol abus; 5, with a contraindication to regional anesthesia; 6, known allergy or hypersensitivity to dexmedetomidine and local anaesthetics; 7, history of nasal operation and nasal diseases, including rhinitis, nasal polyp, and nasosinusitis; 8, cardiovascular comorbidity, including bradycardia and atrioventricular block;

Study & Design

• Study Type: Interventional
• Study Design: Not specified