A clinical trial to find out the genetic association in congenital adrenal hyperplasia
Not Applicable
Completed
- Conditions
- Health Condition 1: E250- Congenital adrenogenital disordersassociated with enzyme deficiency
- Registration Number
- CTRI/2020/05/025128
- Lead Sponsor
- MultiDisciplinary Research Units DHR ICMR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 58
Inclusion Criteria
All Congenital Adrenal Hyperplasia patients due to 21 hydroxylase deficiency attending outpatient endocrine clinic of Government Rajaji Hospital, Madurai
Exclusion Criteria
Non 21 hydroxylase deficiency
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the nature of mutations of CYP21A2 gene in patients with congenital adrenal hyperplasia due to 21 hydroxylase deficiency.Timepoint: To assess the nature of mutations of CYP21A2 gene in patients with congenital adrenal hyperplasia due to 21 hydroxylase deficiency.
- Secondary Outcome Measures
Name Time Method To correlate the various CYP21A2 gene mutations with their clinical expression and the hormonal profile.Timepoint: Two Years