NCT01469104已完成不适用
Metabolic Response to 3-day Fast Versus Carbohydrate-free Diet in Type 2 Diabetes
Minneapolis Veterans Affairs Medical Center2 个研究点 分布在 1 个国家目标入组 7 人开始时间: 2009年8月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 7
- 试验地点
- 2
- 主要终点
- Change in plasma glucose concentration
研究概览
简要总结
The investigators hypothesis is that a carbohydrate-free diet, ingested for 3 days, results in a change in blood glucose that is similar to the change observed after 3 days of fasting.
详细描述
In addition to plasma glucose concentrations, other hormones and metabolites known to be affected by fasting will be measured. These include insulin and glucagon, which are hormones that have an important role in regulating fuel use in the body.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Type 2 diabetes
- •C-peptide > 1.5 ng/ml
排除标准
- •Body mass index > 40
- •hematological abnormalities
- •liver disease
- •kidney disease
- •congestive heart failure
- •life threatening malignancies
结局指标
主要结局
Change in plasma glucose concentration
时间窗: 24 hour profile:before and after meals, or traditional meal times
次要结局
- Change in serum insulin concentrations(24 hour profiles: before and after meals or traditional meal times)
研究者
Frank Q. Nuttall, MD, PhD
Chief, Endocrinology, Metabolism & Nutrition Section, Professor of Medicine
Minneapolis Veterans Affairs Medical Center
研究点 (2)
Loading locations...
相似试验
已完成
不适用
Acute Responses to Manipulating Dietary Carbohydrate Content on Free-living Physical Activity Energy ExpenditurePhysical ActivityNCT03917810University of Bath25
已完成
不适用
The Acute Effects of Caloric Restriction on Anthropometrics, Metabolism, and Cardiovascular Health in Overweight AdultsOverweightIntermittent FastingObesityNCT05422391Skidmore College15
已完成
2 期
The effect of low-carbohydrate diet on inflammatioMetabolic Syndrome.IRCT201105131485N3Vice chancellor for research,Isfahan University of Medical Sciences40
已完成
不适用
Prolonged Fasting on Glucose Metabolism and Hormonal Regulation in Healthy, Obese and Subjects With Type 2 DiabetesHealthyObesityType 2 Diabetes MellitusType 1 DiabetesNCT04283318Medical University of Graz80
已完成
不适用
A randomised controlled trial of a reduced carbohydrate diet versus a low fat diet for the treatment of childhood obesity: the Eat Smart StudyNutritional, Metabolic, EndocrineChildhood obesityISRCTN49438757ational Heart Foundation (Australia)135