Central Sensitization in Patients Seeking Outpatient Physical Therapy Services
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 77
- 试验地点
- 1
- 主要终点
- Pittsburg sleep scale
研究概览
简要总结
This is an observational study to examine presence of CS in patients with knee osteoarthritis (OA), chronic LBP (CLBP), and chronic neck pain (CNP) seeking outpatient physical therapy (PT) services. The study will also examine if outcomes differ between patients with CS and patients without CS symptoms with standard PT interventions.
详细描述
Central Sensitization (CS), defined as augmented pain processing, is common in subgroup of nearly all chronic pain conditions, including fibromyalgia, CLBP, OA, and chronic tension headache. However, current studies of CS are primarily limited to research settings, lacking the knowledge about prevalence of CS and rehabilitation outcomes in usual clinical care.
Practicing clinicians do not routinely assess for CS symptoms. Without proper screening for CS, and lack of knowledge of varying levels of nervous system involvement contributing to pain, clinicians are unable to fully identify the depth of the mechanisms and therefore unable to fully determine the best treatment strategies. This observational study addresses this gap in knowledge by screening patients for CS symptoms.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of knee, neck, or back pain
- •Chronic pain as defined pain > 3 months
- •Able to read and understand English
排除标准
- •Pregnancy
- •Pain less than 3 months
结局指标
主要结局
Pittsburg sleep scale
时间窗: Through study completion, up to 16 weeks
A standard questionnaire to examine sleep problems. A total of 5 scores or greater indicate poor sleep quality
Lower Extremity Functional Scale (LEFS) for patients with knee OA
时间窗: Through study completion, up to 16 weeks
LEFS is a 20-question survey about the participant's ability to perform everyday tasks.
Percentage of patients with knee OA, CLBP, and CNP presenting with CS symptoms.
时间窗: Through study completion, up to 16 weeks
Percentage of patients with knee OA, CLBP, and CNP presenting with CS symptoms.
Functional Exam as part of routine primary PT
时间窗: Through study completion, up to 16 weeks
Routine PT functional assessment includes gait, sit-to-stand, stair climbing, and squats
2011 Fibromyalgia (FM) survey
时间窗: Through study completion, up to 16 weeks
A standard questionnaire for centralized pain. Scores 3-6 in widespread pain index and 9 or greater in symptom severity suggest widespread pain
Oswestry Disability Index (ODI) for patients with CLBP
时间窗: Through study completion, up to 16 weeks
ODI is a 10-question survey in which participants check a box corresponding to how their low back pain impacts their activities of daily living.
Beck Anxiety Inventory
时间窗: Through study completion, up to 16 weeks
A standard questionnaire with 21 questions. Scores 0-21=low anxiety, scores 22-35=moderate anxiety and scores 36 and above=potentially concerning level of anxiety
Fear Avoidance Questionnaire
时间窗: Through study completion, up to 16 weeks
A standard questionnaire to examine fear related to work and physical activities.
Physical Therapy examination data
时间窗: Through study completion, up to 16 weeks
Routine PT subjective and objective examination data that includes history taking, range of motion, muscle testing, and neurological exam if necessary
Neck Disability Index (NDI) for patients with CNP
时间窗: Through study completion, up to 16 weeks
NDI is a 10-question survey in which participants check a box corresponding to how their neck pain impacts their activities of daily living.
Neck flexor muscle performance
时间窗: Through study completion, up to 16 weeks
Strength and endurance. Strength will be tested manually with 0-5 MMT standard grading scale or with use of dynamometer for strength and endurance performance of individual muscles.
次要结局
未报告次要终点
研究者
Neena Sharma, PT, PhD, CMPT
Principal Investigator
University of Kansas Medical Center