Diagnostic accuracy of spectral computed tomography for detection of flow limiting coronary stenosis using fractional flow reserve as the standard of reference - CLARITY study

niversitair Medisch Centrum Utrecht0 个研究点目标入组 75 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•- >=18 years old;
•- Suspected or known stable angina with pre-test likelihood of 50-85% using the method recommended by the European Society of Cardiology 2013 Guidelines on the management of stable coronary artery disease (Eur Heart J 2013);
•- Referred for invasive testing with fractional flow reserve;
•- Willing and able to give informed consent.

•- Subjects with suspected or known stable angina with pre-test likelihood of 0-50% using the method recommended by the European Society of Cardiology 2013 Guidelines on the management of stable coronary artery disease (Eur Heart J 2013);
•- Subjects who because of age, general medical or psychiatric condition, or physiologic status cannot give valid informed consent or tolerate the coronary CTA examination;
•- Subjects with (severe) renal insufficiency, indicated as glomerular filtration rate (GFR) <60 ml/min;
•- Subjects with unknown GFR or obtained >3 months before the planned scan;
•- Contraindication or allergy to intravenous contrast agent(s);
•- Subjects who participate in an other study with radiation which is estimated to be in risk category III (ICRP 62);
•- Subjects who are pregnant;
•- Subjects with contraindications to cardiac CT and/or step and shoot protocol, betablockers, adenosine or nitroglycerine.

发起方

niversitair Medisch Centrum Utrecht