Treatment of Migraine through Ayurvedic line of Management

Phase 3

Not yet recruiting

Conditions: Migraine without aura. Ayurveda Condition: ARDHAVABEDAKAH,

Registration Number: CTRI/2022/08/044781

Lead Sponsor: Department Of Shalakya Tantra

Brief Summary: *Ardhavabhedaka* is a *shiroroga1*characterized with severe *sambheda* (piercing), *toda* (pricking), *shula*(pain), *bhrama* (giddiness) in one half side of the head. It relapses suddenly after ten days orfortnight. According to *acharya Sushruta*, it is *tridoshaja2*and according to *acharya Charaka* it is *vataja or vata-kaphaja3*.Ayurveda emphasizes various treatment modalities of *ardhavabhedaka* whichincludes *Snehana* (oleation), *Swedana* (fomentation), *virechana* (purgation),*Dhoopana* (fumigation)and *Sneha Bhojanam* (unctuous food)*4*.*Ardhavabhedaka* can be co-related with migraine.

Migraine is achronic neurological disease characterized by recurrent, moderate to severeheadaches often in association with autonomic nervous system symptoms.According to International Headache Society, migraine constitutes 16% of theprimary headache and affects 10-20% of the general population. It is threetimes more common in women than men, it is underdiagnosedand undertreated, hence WHO ranks Migraine among the Worldâ€™s most disablingmedical illness5. Current line of management advocates the use of analgesicsand anti-emetics in acute attacks. If not responding, vasoconstrictor like Argotalkaloids are given. Sumatryptan has been used more successfully. Prophylaxisof migraine may be achieved by Topiramate, Flunarizine and Propranalol etc6.

Eventhough a lot of research on migraine with different treatment modalities hasbeen undergoing in bio-medical world, considerable number of worldpopulation is suffering from thisdisease without satisfactory relief. This raises the need to explore aneffective line of management for this disorder.

*Shalaparni* *nasya7* and *Vidangadi**nasya8* have been mentioned for *Ardhavabhedaka Chikitsa.**Shalaparni* is *tikta madhura Rasa, guru Guna, ushna Virya, madhuraVipaka* and *Tridoshahara. Vidanga* is *katu kashaya Rasa, laghu rukshatikshna sara Guna, ushna Virya, katu Vipaka,* and *Kaphavatahara* innature and *Krishna Tila* is *madhura Rasa, guru snigdha Guna, ushna Virya, madhuraVipaka* and *Tridoshahara* in nature.

Hence, presentstudy is being taken up to evaluate the effect of *Shalaparni Avapidana Nasya*in the management of *Ardhavabhedaka. Vidangadi Avapidana Nasya* will betaken as control drug.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

Patients having the clinical features of Ardhavabhedaka (migraine without aura).
Patients aged between 16-60 years of either gender.
3.Patients suitable for Nasya Karma.

Exclusion Criteria

Patients having history of a head trauma and other type of headache.
Patients with other systemic disorders like hypertension, diabetes mellitus etc.
â€¢Pregnant women and lactating mothers.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To Observe Reduced in headache, nausea, photophobia and phonophobia	In 7 Days

Secondary Outcome Measures

Name	Time	Method
To Observed Complete reduction in headache, nausea, photophobia, phonophobia	In 21 Days

Trial Locations

Locations (1): Shree Jagadguru Gavisiddeshwara Ayurvedic Medical College Post Graduate Studies And Research Centre
🇮🇳
Koppal, KARNATAKA, India
Shree Jagadguru Gavisiddeshwara Ayurvedic Medical College Post Graduate Studies And Research Centre
🇮🇳Koppal, KARNATAKA, India
Dr Syed Rasool Sufiyan
Principal investigator
8123101883
syedrasoolsufiyan7@gmail.com