Effectiveness of Magnetic Stimulation of Brain In Treatment of functional neurological symptom disorder (seizure type)

Not Applicable

Conditions: Health Condition 1: F445- Conversion disorder with seizuresor convulsions

Registration Number: CTRI/2023/03/050710

Lead Sponsor: Sri Guru Ram Rai Institute Of Medical And Health Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1.Patient with a diagnosis of FND-S, based on the diagnostic criteria of diagnostic and statistical manual of mental disorder, fifth edition (DSM 5) or international classification of disease (ICD 11) and confirmed by video EEG monitoring or video monitoring.

2.Patient aged between 15-59 years.

3.Patient with diagnosis of PNES with monthly frequency of >3 seizures (for at least a month).

4.Patient giving written consent to participate in protocol. For an adolescent, sample consent will be taken from the guardian.

5.Normotensive patients.

6.Patients not receiving any psychotherapy in last one month.

Exclusion Criteria

1.Patient is uncooperative for the procedure.

2.Patient with history of previous or current epilepsy

3.Patients receiving ECT in past 6 months.

4.Patient with severe mental disorders (SMD).

5.Patient with implanted metallic devices.

6.Any co morbid substance use disorders except nicotine and caffeine (as per DSM 5).

7.Patient with other neurovascular comorbidities (tumor,cerebrovascular events (CVE), cranio-encephalic trauma.

8.Significant unstable medical condition like uncontrolled hypertension, complicated diabetes mellitus or any organ failure.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
frequency of dissociative symptoms - PNES SCORE,DESTimepoint: PNES SCORE , DES will be applied at baseline, 7th day and 21st day

Secondary Outcome Measures

Name	Time	Method
To compare the quantitative change in depressive and anxiety symptoms in patients suffering from functional neurological symptom disorder, seizure type following active continuous theta burst stimulation compared with sham stimulation. <br/ ><br> <br/ ><br>To study the correlation among changes if any in dissociative, socio-demographic variables, depression, anxiety scores and other clinical measures following active continuous theta burst stimulation in patients suffering from functional neurological symptom disorder, seizure typeTimepoint: HADS, CGI, WHO-QOL BREF will be applied at baseline, 7th day and 21st day