Study on Transfusion Effects in Preterm infants
- Conditions
- 1001796910002086neurologische ontwikkelingAnemia and low red blood cell count
- Registration Number
- NL-OMON48979
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 67
- gestational age < 32 weeks
- before 7 days of age
- written informed consent by legal representative(s)
- Chromosomal abnormality (e.g. trisomy 13, 18, 21)
- Perinatal asphyxia resulting in Apgar score (AS) < 5 at five minutes
postpartum
- Major congenital malformations that increase the risk of death or adverse
neurodevelopmental outcome (congenital cerebral malformations, congenital heart
diseases excluding patent ductus arteriosus)
- Intraventricular and periventricular hemorrhage > grade 2 according to
Papile, prior to inclusion
- Diagnosis of NEC prior to inclusion
- Alloimmune hemolytic disease, sickle-cell disease or thalassemia
- Any received RBC transfusions prior to inclusion
- Inability to understand Dutch by the parents
- Parents expressing strong philosophical or religious objections to
transfusion
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method