Labor Analgesia With Ropivacaine and Clonidine

Completed

• Conditions: Labor Pain
• Interventions: Drug: ropivacaine; Drug: ropivacaine and clonidine

• Registration Number: NCT00626977
• Lead Sponsor: UPECLIN HC FM Botucatu Unesp

Brief Summary

The aim of the present study was to examine, for pain relief during labor, the efficacy of two pharmacological approaches - the 0.125% ropivacaine alone and the 0.0625% ropivacaine added to 75 ug clonidine, both by epidural administration. The effect of the drugs on mother and newborn was also determined.

Detailed Description

Not available

Study Timeline

• Study Start: 2000-05
• Primary Completion: 2000-05
• Study Completion: 2001-12
• Status Verified: 2008-02
• Study First Submitted: 2008-02-20
• Study First Submitted QC: 2008-02-28
• Study First Posted: 2008-02-29
• Last Update Submitted: 2015-07-07
• Last Update Posted: 2015-07-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Singleton healthy
• Full-term pregnancy
• American Society of Anesthesiologists physical status I or II

Read More

Exclusion Criteria

• Patients who had received opioids
• History of hypersensitivity to local anesthetic or to clonidine
• Fetus showed signs of possible intrauterine suffering
• Fetus showed signs of possible neurological deficit

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
R	ropivacaine	R group:15 mL of 0.125% ropivacaine (18.75 mg)
RC	ropivacaine and clonidine	RC group:0.0625% ropivacaine (9.375 mg) plus 75 ug clonidine

Trial Locations

Locations (1)

College of Medicine of Botucatu; 🇧🇷 Botucatu, São Paulo, Brazil