Role of platelet rich plasma and prolotherapy in pain of patients with knee osteoarthritis
Phase 2
- Conditions
- Health Condition 1: S818- Open wound of lower leg
- Registration Number
- CTRI/2021/11/038195
- Lead Sponsor
- King Georges Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients giving written consent will be taken, Patient in the age group of 40 to 70 years.Knee osteoarthritis grade I & II (According to Kellgren et al classification scale)
Exclusion Criteria
Patients not giving informed consent, Knee osteoarthritis grade III to IV (According to Kellgren et al classification scale),Patients with rheumatoid arthritis or hemophilia, previous history of knee surgery, drug or alcohol addiction, and use of anticoagulant or nonsteroidal anti-inflammatory drugs (NSAIDS) in previous 7 days.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ï?§After injection patient will be offered acetaminophen tablets to use as needed for up to 1 week and advise knee rest for 2 -4 days with progressive resumption of routine activity over 1 month <br/ ><br>ï?§They will be discouraged from using NSAIDS and start new therapies for their OA during study period <br/ ><br>Timepoint: VAS & WOMAC Score at 1 week, 1month, 3months & <br/ ><br>6months.
- Secondary Outcome Measures
Name Time Method ï?§Followup will be done through OPD visits and regular mobile communication to ask regarding pain relief until 24 week and grading pain relief with respect to VAS and WOMAC scoreTimepoint: 24 week and grading pain