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Clinical Trials/NCT04558801
NCT04558801
Completed
Not Applicable

The Effects of a Mobile Application-based Lifestyle Counselling on Body Weight Loss in Obese Subjects

University of Oulu1 site in 1 country200 target enrollmentOctober 12, 2020
ConditionsObesity

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity
Sponsor
University of Oulu
Enrollment
200
Locations
1
Primary Endpoint
Change in body weight
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

The aim of the trial is to study the effect of a mobile application-based lifestyle change program on body weight loss in adult subjects with obesity. The main focus is to motivate and support beneficial lifestyle changes targeting long-term weight management.

This study comprises two randomly assigned study arms: mobile application-based lifestyle change program and "waiting-list" control. The mobile application-based lifestyle change program consists of twice a week content for the first 6 months, continuing with less frequent contents for the following 6 months (the length of intervention 12 months). The "waiting-list" control group will receive mobile application-based lifestyle change program after 6 months followed by intervention for 12 months. The main aim is to demonstrate that the users of mobile application-based lifestyle change program lose more weight than controls at 6 month timepoint and weight loss is maintained for 18 months (6 months after the end of mobile application-based lifestyle change program use). Weight is measured and blood samples (lipids, glucose and metabolic syndrome measures) are collected at 0, 6, 12, and 18 months.

The mobile application-based counselling contains aspects of cognitive behavior therapy and persuasive system design and consists of twice a week reminders, tasks, self-monitoring, and reflection.

The main outcome is the decrease in body weight. Secondary outcomes are changes in eating behavior, psychological factors, components of metabolic syndrome (waist circumference, plasma lipid and glucose values, blood pressure), and calculated scores of metabolic condition and adiposity.

Registry
clinicaltrials.gov
Start Date
October 12, 2020
End Date
October 31, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Factorial
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Janne Hukkanen

Professor of Internal Medicine

University of Oulu

Eligibility Criteria

Inclusion Criteria

  • Body mass index 30 to 40 kg/m2
  • Ownership of a smartphone

Exclusion Criteria

  • Untreated hypothyroidism
  • Oral glucocorticoid treatment
  • Pregnancy or lactation
  • No possibility to use mobile phone or tablet
  • No knowledge of Finnish language
  • Presumed lack of adherence to the study
  • Participation in another ongoing weight management program
  • Diagnosed or suspicion of cardiovascular disease causing restrictions to exercising
  • Bariatric operation planned
  • Usage of any anti-obesity drug

Outcomes

Primary Outcomes

Change in body weight

Time Frame: Baseline to 6 months

Secondary Outcomes

  • Change in eating behavior(Baseline to 6 months)
  • Change in body weight(Baseline to 18 months)
  • Change in blood pressure(Baseline to 6 months)
  • Change in waist circumference(Baseline to 6 months)
  • Change in metabolic syndrome status(Baseline to 6 months)

Study Sites (1)

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