Multifunctional Substrate for Early Detection of Oxidative Stress Susceptibility and Application to Parkinson's Disease

• Conditions: Parkinson's Disease; Oxidative Stress

• Registration Number: NCT00271141
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The proposed work is based on the detection of a novel molecule for sensitivity to oxidative stress in humans in venous blood

Detailed Description

Since alterations in mitochondrial functions in platelets and lymphocytes have been detected in Parkinson's disease we plan to monitor the metabolism a a new molecule (LTG) in the blood samples of Parkinson's disease patients and compare them to controls. We shall use 10 cc of venous blood and analyze serum, white blood cells and platelets. We shall not extract nor use DNA.The main purpose is to develop a marker for Parkinson's disease in venous blood.

Study Timeline

• Study Start: 2005-05
• Status Verified: 2005-12
• Study First Submitted: 2005-12-29
• Study First Submitted QC: 2005-12-29
• Last Update Submitted: 2005-12-29
• Study First Posted: 2005-12-30
• Last Update Posted: 2005-12-30
• Study Completion: 2015-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

Parkinson's disease Healthy control -

Exclusion Criteria

None -

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel