A New Exogenous Marker for Diagnosis of Oxidative Stress During Laproscopic Surgery
Not Applicable
- Conditions
- Oxidative StressLaproscopy
- Registration Number
- NCT01393587
- Lead Sponsor
- Western Galilee Hospital-Nahariya
- Brief Summary
Recently, a new synthetic marker was developed, based on a molecule that is composed of Amino Acids and Linoleic Acid and Neucleic Acid, which is capable of detecting even minor changes of oxidative stress.
The investigators would like to assess the usefulness of this marker during positive pressure pneumoperitoneum, during laproscopic surgery, with or without intenstinal resection (ischemia induced by intra-abdominal pressure and vascualr compromise).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Healthy patients undergoing elective laproscopic cholecystectomy and patients undergoing operation for tumer of large intenstine.
Exclusion Criteria
- Patients suffering from Cardio Pulmonory and renal diseases
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the synthetic marker's detection of oxidative stress in laproscopic surgery?
How does the new exogenous marker compare to traditional oxidative stress indicators like MDA or 8-OHdG in laparoscopic settings?
Are there specific biomarkers that correlate with the synthetic marker's response during pneumoperitoneum-induced ischemia?
What adverse events are associated with blood sampling during laproscopic procedures and how are they managed?
What other compounds or biomarkers are being explored for monitoring oxidative stress in minimally invasive abdominal surgeries?
Trial Locations
- Locations (1)
Western Galilee Hospital
🇮🇱Nahariya, Israel
Western Galilee Hospital🇮🇱Nahariya, IsraelAmitai Bickel, Dr.Principal Investigator