Red Cell Distribution Width and Lactate Albumin Ratio as Prognostic Markers for Mortality in Sepsis and Septic Shock Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- The prediction of mortality
研究概览
简要总结
The aim of this study is to find the utility of red cell distribution width and lactate/albumin ratio as prognostic markers in sepsis and septic shock patients.
详细描述
Several indicators are being used to predict the prognosis of sepsis. Commonly used prognostic indicators include Acute Physiological and chronic health evaluation II (APACHE II), Sequential Organ Failure Assessment (SOFA), Mortality in Emergency Department Score (MEDS), New York Sepsis severity score.
Red cell distribution Width and lactate albumin ratio are being investigated for there prognostic value in septic patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age from 18 to 60 years old.
- •Clinical criteria of sepsis
- •Or clinical criteria of septic shock including sepsis with persisting hypotension requiring vasopressors to maintain mean arterial pressure > 65 mmHg and having a serum lactate level > 2 mmol/L despite adequate volume resuscitation.
排除标准
- •No informed consent.
- •Patient with incomplete information and data.
- •The patient who received blood transfusion within 90 days before emergency admission.
- •The patients who are known to have long-term conditions causing anemia like sickle cell anemia, thalassemia, iron deficiency anemia.
- •Malignancy and chemotherapy during the previous 90 days.
- •Patients with either hepatic dysfunction, renal failure, having any disease in which albumin should be supplemented as liver cirrhosis with ascites, nephrotic syndrome and burns.
结局指标
主要结局
The prediction of mortality
时间窗: 28 days
The diagnostic accuracy for prediction of 28th day mortality by Red cell distribution Width and lactate albumin ratio.
次要结局
- Length of intensive care stay(28 days or till discharge from intensive care.)
- Extent of organ dysfunctions in patients with severe sepsis and septic shock(28 days)
研究者
Shimaa Saad Mohamed Awd
Assistant lecturer
Tanta University