NL-OMON54042
Recruiting
Not Applicable
Magnetic Resonance imaging-guided high intensity focused ultrasound for patients with Desmoid-type fibromatosis - MAGNIFIED trial
niversitair Medisch Centrum Utrecht0 sites13 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- aggressive fibromatosis
- Sponsor
- niversitair Medisch Centrum Utrecht
- Enrollment
- 13
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Patients \> 18 years
- •\- Histological evidence of DTF
- •\- Patients with failure of active surveillance\* for their present manifestation
- •\- Desmoid tumour must be targetable with MR\-HIFU device
- •\- Desmoid tumour must be visible on pre\-treatment MR\-imaging
- •\- Patient is able to fit in the MRI gantry
- •\- Capable to understand and sign informed consent
- •\*failure of active surveillance due to tumor growth and/or new or worsening
Exclusion Criteria
- •\- Personal or family history of familial adenomatous polyposis (FAP)
- •\- Intra\-abdominal tumour localization
- •\- Patients with a tumour greater than 10 centimetres (as measured on MRI by a
- •radiologist)
- •\- Patients who have undergone prior active treatment (systemic therapy,
- •radiotherapy, prior ablation) for the present manifestation of DTF
- •\- Patients with recurrent disease within 12 months after treatment for their
- •prior desmoid tumour
- •\- Patients weighing more than 140 kilograms
- •\- Pregnancy
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
Magnetic Resonance imaging-guided high intensity focused ultrasound for patients with Desmoid-type fibromatosisNL-OMON23077MC Utrecht13
Completed
Not Applicable
Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases - a Multicenter Study.bone disseminations.Bone metastases1000594210027476NL-OMON39361Philips Medical Systems, MR Finland14
Recruiting
Phase 4
A study to test the efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound in reducing pain associated with painful bone cancerCTRI/2013/04/003572Philips Medical Systems MR Finland62
Completed
Not Applicable
High-field magnetic resonance imaging in multiple sclerosisMSMultiple Sclerosis10012303NL-OMON32247Vrije Universiteit Medisch Centrum120
Recruiting
Not Applicable
Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancerbreast cancermalignant breast tumor100062911000623210006295NL-OMON55791niversitair Medisch Centrum Utrecht50