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The Effect of Time Restricted Feeding on Fat Mass in Overweight Women

Not Applicable
Conditions
Weight Loss
Interventions
Behavioral: Time restricted feeding
Registration Number
NCT02629900
Lead Sponsor
University of Western Ontario, Canada
Brief Summary

Participants will complete a one-month intervention where they are will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours. During the remaining 16-hour intermittent fasting period (2000 to 1200 hours) participants will be allowed to drink zero calorie beverages (diet soda pop, black coffee, tea, water, etc) in order to maintain normal hydration. There will be no attempt to restrict food intake. Rather simply to restrict the time period each day when food is consumed. Participants' body mass, fat mass, and non-fat mass will be monitored non-invasively using a weigh scale and densitometry via air displacement (Bod Pod) at 0, 2 and 4 weeks following the dietary intervention. Also, participants will be interviewed following the final body composition measure to assess whether or not they continued to follow the intermittent fasting approach.

Detailed Description

Participants (16 overweight women, BMI (Body mass index) ˃25, ages 18- 30 y)will complete a one-month intervention where they will restrict their daily food intake to an 8-hour time period, i.e., between 1200 to 2000 hours. During the remaining 16-hour intermittent fasting period (2000 to 1200 hours) participants will be allowed to drink zero calorie beverages (diet soda pop, black coffee, tea, water, etc) in order to maintain normal hydration. There will be no attempt to restrict food intake. Rather simply to restrict the time period each day when food is consumed. Participants' fat mass will be monitored non-invasively using densitometry (with a Bod Pod) prior to and following a 4 week intervention where the participants will eat their normal daily intake during an 8-hour period each day (1200 to 2000 hours). The Bod Pod measures body volume via air displacement and together with an accurate measure of body mass enables body density to be calculated (Density = mass/volume). Satisfaction, hunger, and fullness with the diet will be monitored on a weekly basis using a validated visual analog scale (Flit et al, 2000). Adherence to the diet will also be assessed on a weekly basis as the number of days the diet was followed. During the 16-hour fasting period participants will be able to drink as much of zero calorie beverages as they desire. On day 2, 7, 14, 21, \& 28 participants will return to the lab at 8am (following a 12 hour fasting period) and both the acidity of their urine (using a urine dip stick) and their blood sugar (using a glucometer) will be tested. Following one month the participants will be allowed either to continue this eating pattern or revert to their prior 3 meal intake. After a month of self-regulation, the participants' fat mass will be measured again using the Bod Pod.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
16
Inclusion Criteria
  • Asymptomatic participants between the ages of 18-30 years with body mass index ˃25 will be studied
Exclusion Criteria
  • Diabetic
  • Pregnant
  • Individuals with a history of fainting
  • Low blood sugar
  • Heart disease, migranes, or heart burn
  • Participants less then 18 of age
  • Anyone who for health or performance reasons should not skip breakfast will be excluded. These will be assessed by self report

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Intermittent fasting groupTime restricted feedingParticipants will restrict their daily food intake (time restricted feeding) to an 8-hour time period between 1200 to 2000 hours. During the remaining 16-hour intermittent fasting period (2000 to 1200 hours) participants will be allowed to drink zero calorie beverages (diet soda pop, black coffee, tea, water, etc) in order to maintain normal hydration. There will be no attempt to restrict food intake. Rather simply to restrict the time period each day when food is consumed.
Primary Outcome Measures
NameTimeMethod
Fat mass change over 4 weeks period of intervention4 weeks

Body fat mass change (%) will be measured using BodPod over the course of 4 weeks at 0, 2 and 4 weeks

Secondary Outcome Measures
NameTimeMethod
Non-fat mass change over 4 weeks period of intervention4 weeks

Body non-fat mass (lean mass) (%) will be measured using BodPod over the course of 4 weeks at 0, 2 and 4 weeks

Urine acidity change over 4 weeks of intervention4 weeks

Urine acidity will be measured following a 12 hours fasting at 0800 using a urine dip stick on days 2, 7, 14, 21, \& 28

Feeling of fullness change over 4 weeks of intervention4 weeks

Feeling of fullness will be monitored on a weekly basis using a validated visual analog scale (Flit et al, 2000)

Diet satisfaction change over 4 weeks of intervention4 weeks

Diet satisfaction will be monitored on a weekly basis using a validated visual analog scale (Flit et al, 2000)

Blood sugar change over 4 weeks of intervention4 weeks

Fasted blood sugar will be measured following a 12 hours fasting at 0800 using a finger prick glucometer (Free Style Lite) on days 2, 7, 14, 21, \& 28

Feeling of hunger change over 4 weeks of intervention4 weeks

Hunger will be monitored on a weekly basis using a validated visual analog scale (Flit et al, 2000)

Trial Locations

Locations (1)

Exercise Nutrition Research Laboratory, Western University

🇨🇦

London, Ontario, Canada

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